The 6th International Bone Fluid Flow Workshop

描述(由申请人提供)： 国际骨液流动研讨会于六年前在纽约开始，每年举行一次。骨流体流动研究已成为骨组织水平、细胞和分子水平对流体流动的响应、在组织工程中的作用以及骨疾病的治疗潜力等与骨相关的各种热点问题的研究热点。以前的IBFF研讨会为讨论与骨骼相关的健康问题中的液体流动效应提供了一个成功的论坛。这些研讨会极大地影响了我们对液体流动在细胞和组织机械转导中的作用的理解。我们即将举行的IBFF会议将于9月9日在华盛顿州西雅图举行。30-2004年10月1日。目前的研讨会旨在为当前和未来的研究方向提供一个学科论坛，在这个令人兴奋的阶段，骨液体流动领域即将探索液体流动对细胞活动的机制，骨液体流动成像，并转化为临床。这个骨液流动研讨会的目标是为包括骨生物学家、工程师和临床医生在内的学科受众激发一个学科计划。这将在五个方面实现。首先，将介绍与通过骨骼的液体流动相关的基本途径的最新突破。第二，将介绍新开发的测量通过骨骼的液体流动的实验和成像方法。第三，将讨论骨液流动中的细胞和分子力学转导和组织工程方面。第四，关键的问题，生理机制和翻译的临床研究与流体通过骨流动将被识别和介绍。第五，注重研究生和青年科研人员的提拔。已经创建了一个网站，用于信息、摘要提交和登记以及其他必要的交流。该网站位于石溪大学，地址为http://bme.sunysb.edu/Bone-Fluid-Flow/。 一个令人兴奋的项目正在计划中，其中包括科学会议。 1.骨内流体流动途径的基本生物学和工程学方面 2.骨内液体流动的成像和实验方法 3.对流体流动刺激的细胞和分子反应 4.流体流动在组织工程中的作用 5.骨液流动的生理机制及临床意义。

DESCRIPTION (provided by applicant): The International Bone Fluid Flow Workshop started six years ago in New York and has been held annually. Bone fluid flow research has become a promising area for various bone related hot topics, e.g., the response to fluid flow on the tissue level as well as the cellular and molecular levels, its role in tissue engineering, and its therapeutic potential for bone disease. Previous IBFF workshops provided a successful forum for the discussion of fluid flow effects in bone related health problems. These workshops have greatly impacted our understanding of the role of fluid flow in cellular and tissue mechanotransduction. Our upcoming IBFF meeting will be held in Seattle, WA, Sept. 30 - Oct. 1, 2004. The current workshop is designed to provide a disciplinary forum at this exciting stage for the current and future research directions, in which the field of bone fluid flow is on the cusp of exploring the mechanism for fluid flow on cellular activities, bone fluid flow imaging, and translation to the clinic. The goals of this Bone Fluid Flow Workshop are to stimulate a disciplinary program for a disciplinary audience including bone biologists, engineers and clinicians. This will be achieved in fivefold. First, recent breakthroughs in fundamental pathways related to fluid flow through bone will be presented. Second, newly developed experimental and imaging approaches to measure fluid flow through bone will be presented. Third, cellular and molecular mechanotransduction and tissue engineering aspects in bone fluid flow will be discussed. Fourth, critical issues of the physiological mechanism and translation of clinical research related to fluid flow through bone will be identified and presented. Fifth, promotion of graduate students and young investigators will be emphasized. A web site has been created for information, abstract submission, and registration, as well as other necessary communication. The site is hosted in Stony Brook University in an address of http://bme.sunysb.edu/Bone- Fluid-Flow/. An exciting program with scientific sessions is planned. 1. Fundamental biology and engineering aspects of fluid flow pathways in bone 2. Imaging and experimental approaches for fluid flow through bone 3. Cellular and Molecular Response to Fluid Flow Stimulation 4. The role of fluid flow in tissue engineering 5. Physiological mechanism and clinical implications of bone fluid flow.