2004 Mechanisms of Toxicity Gordon Research Conference

描述（由申请人提供） 毒性机制戈登研究会议，2004年7月25- 30日，科尔比学院，沃特维尔，缅因州。 戈登研究会议（GRC）在传播和促进毒理学研究方面建立了丰富的优秀传统。 该会议自1958年以来每两年举行一次，现已发展成为关注化学损伤分子机制和环境人类疾病发病机制的首要科学会议。 在过去的几年里，基于该计划的高质量和会议对环境健康科学进步的重大贡献，毒性机制GRC获得了NIEHS的资助。 2004年会议的组织工作包括毒理学领域的最新信息以及该领域新技术和新兴技术的影响。 2004年会议的主题涵盖从细胞表面到细胞核的毒理学反应，包括：i）新兴技术; ii）细胞表面和核受体生物学; iii）对损伤反应的粘附分子调节; iv）对氧化应激反应的脂质信号传导：新概念的翻译; v）蛋白质结构和功能; vi）染色质重塑; vii）细胞凋亡和; viii）细胞周期的十字路口，肿瘤抑制因子和DNA损伤和修复。 该计划包括国际公认的领导人和来自美国和国外的有才华的新调查人员。 时间已分配给初级研究人员介绍他们的工作在晚突破研究和海报会议。 主席和共同主席将鼓励科学和技术领域的讨论和对话，以最大限度地扩大参与，并增加高级和初级调查人员、博士后研究员和学生之间的互动。 因此，2004年的会议将继续作为毒理学领域唯一领先的小型会议而发展。

DESCRIPTION (provided by applicant) Mechanisms of Toxicity Gordon Research Conference, July 25-30,2004, Colby College, Waterville, Maine. The Mechanisms of Toxicity Gordon Research Conference developed (GRC) has developed a rich tradition of excellence in the dissemination and promotion of research in the toxicological sciences. The conference has been held biennially since 1958 and has evolved to become the premier scientific meeting focusing on molecular mechanisms of chemical injury and the pathogenesis of environmental human disease. The Mechanisms of Toxicity GRC has received funding from NIEHS in past years based on the high quality of the program and the significant contributions of the meeting to the advancement of environmental health sciences. The 2004 conference has been organized to include the latest information in the field of toxicology and the impact of novel and emerging technologies in the field. The topics to be covered in the 2004 conference span the spectrum of toxicological responses from the cell surface to the nucleus and include: i) New and Emerging Technologies; ii) Cell Surface and Nuclear Receptor Biology; iii) Modulation of Adhesion Molecules in Response to Injury; iv) Lipid Signaling in Response to Oxidative Stress: Translation from New Concepts; v) Protein Structure and Function; vi) Chromatin Remodeling; vii) Apoptosis and; viii) Crossroads of the Cell Cycle, Tumor Suppressors and DNA Damage and Repair. The program includes internationally recognized leaders and talented new investigators from the United States and abroad. Time has been allotted for junior investigators to present their work in Late Breaking Research and Poster Sessions. Chairs and co-Chairs will stimulate discussion and dialogue scientific to maximize participation and increase interactions among senior and junior investigators, postdoctoral fellows and students. Thus, the 2004 conference is poised to continue its growth as the single leading small conference in toxicology.