2003 Oxygen Radicals in Biology Gordon Conference

描述（由申请人提供）：戈登“生物学中的氧自由基”研究会议旨在为环境毒理学家、生物学家、生物化学家、细胞生物学家、临床医生和其他生物医学科学家提供有关活性氧物种及其与其他自由基（包括一氧化氮）相互作用的最新知识，以及对环境毒物的生物反应和慢性疾病的病因学。该研究会议每两年举行一次；下次会议将于2004年2月8日至13日在加州文图拉的文图拉海滩万豪酒店举行。自1981年以来已经举行了12次会议，根据大量的申请者和会后评价，这些会议证明是极具成效的。所要求的经费部分用于支付来自美国的发言者和富有成果的研究生/博士后候选人的旅费、生活费和注册费。本计划所列的演讲者是根据往届会议主席、联席主席和与会者的建议选出的。演讲者被邀请介绍他们在生物学中氧自由基的最新研究。主题包括：抗氧化剂的作用机制；蛋白质氧化的机制和后果；巯基氧化还原状态与细胞功能的调节；氧化还原细胞信号在环境暴露于毒素的背景下心血管和神经退行性疾病。此外，Bruce Freeman教授将作题为“从黄嘌呤氧化酶到一氧化氮；自由基在流通。”预计将有50至70张海报，分别举行两次为期两天的宣传活动。根据戈登会议的规定，总出席人数不得超过135人。戈登会议为与会者和研究领域的多样性提供了一个极好的和急需的论坛。这次戈登研究会议的主要优势是为不同学科的科学家提供了以扩展和不间断的方式进行互动的机会。这种类型的互动通常会产生新的合作研究计划。戈登生物学中氧自由基研究会议在探索这一重要领域的前沿研究方面发挥着至关重要的作用，这些前沿研究与了解环境暴露和慢性疾病发生的分子事件有关。

Description (provided by applicant): The Gordon Research Conference on "Oxygen Radicals in Biology" is designed to provide environmental toxicologists, biologists, biochemists, cell biologists, clinicians, and other biomedical scientists with state of the art knowledge on reactive oxygen species and their interactions with other radicals, including nitric oxide, in the biological responses to environmental toxicants and the etiology of chronic diseases. This research conference is held every two years; the next meeting will be held February 8-13, 2004 at the Ventura Beach Marriot Hotel, Ventura, California. Twelve conferences have been held since 1981 and they have proven to be extremely productive based on the large number of applicants and the post-meeting evaluations. Funds are requested to partially support travel subsistence and registration costs for speakers from the United States and productive graduate students/post-doctoral candidates. The speakers listed in this program were selected based on the suggestions from the previous chairs, co-chairs and attendees at the past conference. Speakers have been invited to present their latest research on oxygen radicals in biology. Topics to be covered include: mechanisms of action of antioxidants; mechanism and consequences of protein oxidation; the regulation of thiol redox state and cellular function; the redox cell signaling in the context of environmental exposure to toxins; and cardiovascular and neurodegenerative diseases. In addition, Professor Bruce Freeman will present a Plenary Lecture entitled: "From Xanthine Oxidase to Nitric Oxide; Radicals in Circulation." Two separate poster sessions of two days each are scheduled for an anticipated 50-70 posters. Total attendance is limited to 135 by Gordon Conference rules. The Gordon Conference provides an excellent and much needed forum for the diversity of both participants and research areas. The main strength of this Gordon Research Conference is the opportunities offered for scientists in different disciplines to interact in an extended and uninterrupted fashion. This type of interaction generally results in new collaborative research initiatives. The Gordon Research Conference on Oxygen Radicals in Biology plays a crucial role in exploring frontier research in this important field relevant to understanding of the molecular events that occur on environmental exposure and chronic disease.