课题基金 / 基金详情

CORE--MYOCARDIAL CELL BIOLOGY AND VIRAL VECTOR FACILITY

CORE--MYOCARDIAL CELL BIOLOGY AND VIRAL VECTOR FACILITY
核心——心肌细胞生物学和病毒载体设施
批准号:
7098691
负责人:
Kirk U Knowlton
金额:
$15.69万
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-08-01 至 2007-07-31

项目摘要

项目成果

Kirk U Knowlton的其他基金

相关文献

中文摘要
翻译
描述(由申请人提供): 该计划中的每个项目都将利用细胞生物学核心单元,该单元旨在: 1)提供纯化的新生大鼠心室肌细胞培养物和相关的 在这些细胞中进行基因转移的技术; 2)提供纯化的成年和新生小鼠 来自各种转基因系的心室肌细胞用于分析; 3)产生和利用 用于新生大鼠、成年和新生小鼠中基因转移的重组腺病毒载体 心肌细胞,并为该计划中的各种项目将基因转移到完整的肌肉中; 和4)产生用于基因转移的重组腺相关病毒载体, 肌肉.
英文摘要
DESCRIPTION (provided by applicant): Each of the projects in the program will utilize the Cell Biology Core Unit, which is designed to: 1) to provide purified cultures of neonatal rat ventricular myocardial cells and related techniques for gene transfer in these cells; 2) to provide purified mouse adult and neonatal ventricular muscle cells from various transgenic lines for analysis; 3) to generate and utilize recombinant adenoviral vectors for gene transfer in neonatal rat, adult and neonatal mouse myocardial cells, and for gene transfer into intact muscle for various projects in the program; and 4) to generate recombinant adeno-associated viral vectors for gene transfer in intact muscle.
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Adhesion Molecules of the Intercalated Disc in Cardiomyopathy
Administative Core
Adhesion Molecules of the Intercalated Disc in Cardiomyopathy
Administative Core