Comorbid childhood anxiety and asthma

描述(由调查人员提供)：申请者要求通过以患者为导向的研究生涯发展指导计划获得五年的资助 奖励(K23)计划，以提高她在 焦虑症与哮喘/变态反应并存的调查 青春年华。最终目标是获得两国之间关系的专业知识 焦虑症和哮喘/过敏的并存以及严重的 青年精神病理学，采用纵向、流行病学研究 方法，并最终确定预防性干预措施。这个 申请人在人类发展、临床方面有很强的学术背景 心理学和精神病学流行病学，以及她使用 研究严重精神病风险的发展范式 早发性焦虑症患者提供了一个很好的基础 为了这份工作。拟议的培训目标包括(1)进一步培训以 增加申请者对呼吸道疾病关系的认识 病理生理和焦虑症；(2)高级统计培训和 有纵向数据分析和调查方法的经验，以及； 对整合焦虑研究的潜在干预措施的调查 疾病和哮喘/过敏。这些目标都将有助于申请者 追求创新、全面、技术高效的方法 研究青年时期的这些合并症。该奖项的研究计划分为两个部分 进行四项调查，以补充拟议的培训顺序 活动，并为申请者提供机会探索重要的 流行病学、临床和社区横断面和纵向数据 样本，以及实践经验，在前两项研究中， 申请者将分析以前收集的数据(MECA&SED和Dunedin)。在……里面 第三项研究，申请者将前瞻性地收集她自己的哮喘数据 (网络研究)，正在进行的纵向流行病学临床研究 (精神病学)调查，同时学习如何进行研究。第四次 调查将涉及制定措施和收集试点数据 临床(医学)样本中的哮喘和焦虑。申请者的结果是 ROL将解决上述发展范式，这将是 进一步测试，并将包括早期干预战略，以促进 重症肺炎高危儿童的识别和治疗 精神变态学。这项研究将涉及一项纵向流行病学 旨在降低焦虑症风险的预防性干预研究 在儿童哮喘/过敏患者中。

DESCRIPTION (provided by investigator): The applicant is requesting five years of funding through the Mentored Patient-Oriented Research Career Development Award (K23) program to enhance her technical and methodological skills in the investigation of the co-occurrence of anxiety disorders and asthma/allergy in youth. The ultimate goal is to gain expertise in the relationship between the co-occurrence of anxiety disorders and asthma/allergy and the risk of severe psychopathology among youth, using longitudinal, epidemiologic research methodology and ultimately to identify preventive interventions. The applicant's strong academic background in human development, clinical psychology, and psychiatric epidemiology, and her research experience using a developmental paradigm to study risk for severe psychopathology among individuals with early-onset anxiety disorders provide an excellent foundation for this work. The proposed training goals include (1) further training to increase the applicant's knowledge of the relationship between respiratory pathophysiology and anxiety disorders; (2) advanced statistical training and experience with longitudinal data analysis and survey methods, and; (3) investigation of potential interventions that integrate research on anxiety disorders and asthma/allergy. These goals will all facilitate the applicant's pursuit of innovative, comprehensive, technologically efficient approaches to study these comorbidities in youth. The research plan for this Award is divided into four investigations which complement the proposed sequence of training activities and offer the applicant the opportunity to explore important cross-sectional and longitudinal data from epidemiologic clinical and community samples, as well as hands-on experience, in the first two studies, the applicant will analyze previously collected data (MECA & SED and Dunedin). In the third study, the applicant will collect her own asthma data prospectively (Network study), in an ongoing longitudinal epidemiologic clinical (psychiatric) investigation, while learning how to conduct a study. The fourth investigation will involve developing measures and collecting pilot data on asthma and anxiety in a clinical (medical) sample. The applicant's resulting ROl will address the developmental paradigm described above, which will be further tested and will include early intervention strategies to facilitate the identification and treatment of children who are at risk for severe psychopathology. That study will involve a longitudinal epidemiologic preventive intervention study aimed at reducing the risk of anxiety disorders among pediatric asthma/allergy patients.