VOCABULARY MANAGEMENT FOR CLINICAL RESEARCH DATABASES

提案（改编自申请人摘要）：本申请提出了一个 医疗信息学领域的职业发展计划，涵盖临床 计算机科学和医学。 长期目标是 提交是为了启动一个独立的研究计划，旨在确定 计算机化通用数据项的组织和结构模型 临床研究数据的测量。 本研究的总体目标是 帮助标准化临床试验数据，从而改善以患者为导向的 研究并增加研究向临床实践的转化。 在完成预防医学的临床培训后， 参加了为期两年的医学信息学博士后奖学金。 在此期间，候选人获得了计算机方面的经验和专业知识 科学和临床计算研究问题，如临床数据库 开发和设计。 自2000年7月1日起，候选人将成为 YCMI的助理教授。 这个职业奖将提供宝贵的 支持候选人继续发展相关领域的专门知识 计算机科学和以病人为导向的卫生服务研究，并 作为一名初级教员， 会员是否 一群杰出的导师和顾问已经聚集在一起， 就候选人的研究方向提供指导， 长期职业目标，并就道德行为提供建议和咨询 的研究。 职业发展计划包括额外培训， 包括计算机科学领域的课程作业和密集讲习班， 调查医学和先进的卫生服务研究。 本文提出的研究计划包括：1）建立先进的信息学 用于搜索和组织临床数据库的内部数据字典的工具 研究数据库（试验/DB）和整合标准化临床 词汇表到Trial/DB中; 2）开发允许相关数据项的模型 以有组织的方式进行维护，从而促进未来的合作， 分享; 3）与目前使用的临床研究者合作 试用/数据库用于测试、改进和改进上面开发的工具和模型， 正在进行的或新的研究的背景。

PROPOSAL (Adapted from the applicant's abstract): This application presents a career development plan in the field of Medical Informatics, spanning clinical trials, computer science and medicine. The long-term objective of this submission is to launch an independent research program aimed at identifying models of organizing and structuring generic data items for computerized measurements of clinical research data. The overall goal of this research is to help standardize clinical trials data, thereby improving patient-oriented research and increasing the translation of research into clinical practice. After completing clinical training in preventive medicine, the candidate participated in a two-year postdoctoral fellowship in Medical Informatics. During this time, the candidate gained experience and expertise in computer science and clinical computing research issues such as clinical database development and design. As of July 1, 2000, the candidate will become an Assistant Professor in the YCMI. This career award will provide invaluable support for the candidate to continue to develop expertise in relevant areas of computer science and patient-oriented health services research, and to achieve the immediate goal of scientific independence as a junior faculty member. An outstanding group of mentors and advisors have been assembled who will provide guidance with respect to the direction of the candidate's research and long-term career goals, and provide advice and counsel on the ethical conduct of research. The career development plan includes additional training to include coursework and intensive workshops in the areas of computer science, investigative medicine, and advanced health services research. The research plan presented below involves: 1) building advanced informatics tools for searching and organizing the internal data dictionary of a clinical research database (Trial/DB) and integrating standardized clinical vocabularies into Trial/DB; 2) developing models that allow related data items to be maintained in organized ways, thus promoting future collaboration and sharing; and 3) collaborating with clinical investigators currently using Trial/DB to test, refine, and improve the tools and models developed above in the context of ongoing or new studies.