Neurodegenerative diseases and neural repair

描述(由申请人提供)： 神经退行性疾病对国家的健康和经济有重大影响。认识到这一事实，佐治亚医学院有一个长期目标，即在校园内招募和培养一批核心神经学家，以促进我们对这些严重疾病的生物学和分子基础的了解。通过战略规划和强有力的机构支持，校园里现在已经建立了一个教员核心，他们配备了一系列广泛的技术和模型，可以专注于这些复杂疾病的研究。著名科学家罗伯特·余领导着这支神经科学家队伍。我们现在已经到了成长点，NIH赞助的培训赠款的实施将不仅有利于我们研究目标的实现，而且在全球范围内，通过培训未来的神经科学家来促进科学的持续进步。在此，我们请求为3名博士后和1名博士后实习生提供支持，重点是招聘少数族裔候选人。每个实习生将由该计划的一名教职员工指导，他们在培训方面拥有丰富的经验，并得到全国认可。培训将通过每周的实验室会议和由共同调查员组成的指导委员会进行监测和指导。杰出的神经学家也将每年对该计划的目标、成就和进展进行外部审查。由于该领域需要临床和基础神经科学家，培训计划的目标是培养精通与神经退行性疾病及其修复研究相关的多个领域的博士和医学博士/博士。拥有强大的机构支持、优秀的核心资源和经验丰富的师资队伍，这些关键要素都已具备，可以实施强有力的培训计划。因此，NIH的支持将有助于加强神经科学项目，该项目在推进神经退行性研究领域和培训未来领导者方面具有独特的地位。

DESCRIPTION (provided by applicant): Neurodegenerative disorders have a significant health and economic impact upon the nation. In recognition of this fact, the Medical College of Georgia has had a long-term goal of recruiting and fostering the growth of a core of neuroscientists on campus so as to advance our understanding of the biological and molecular basis of these critically important disorders. Through strategic planning and strong institutional support, a nucleus of faculty are now in place on campus, which are equipped with a wide array of techniques and models that can be focused on the study of these complex disorders. An eminent scientist, Robert Yu, leads this cadre of neuroscientists. We have now reached the point of growth where the implementation of a NIH-sponsored training grant would be beneficial, not only to the achievement of our research goals, but also on a global scale, to the continued advancement of science through the training of future neuroscientists. Here, we request support for 3 post- and 1 predoctoral trainees, with an emphasis on the recruitment of minority candidates. Each trainee will be mentored by one of the Program faculty, who have extensive experience in training and are nationally recognized. Training will be monitored and guided by weekly lab meetings, and by a Steering Committee composed of the co-investigators. Outside review of the program goals, achievements and progress by eminent neuroscientists will also occur annually. Since clinical and basic neuroscientists are needed in the field, it is the goal of the training program to produce PhDs and MD/PhDs who are well versed in multiple areas related to the study of neurodegenerative diseases and their repair. With strong institutional support, excellent core resources, and an experienced faculty, the key elements are all in place for a strong training program. Support by the NIH would thus help strengthen a neuroscience program that is uniquely positioned to both advance the field of neurodegenerative research and train its future leaders.