Screening and Brief Advice to Reduce Teen Substance Use

描述（由申请人提供）： 本竞争性补充申请提交给NIDA，以响应PAS-03-023，药物成瘾国际研究合作。它将在哈佛医学院/波士顿儿童医院青少年药物滥用研究中心（CeASAR）和捷克共和国药物滥用评估、预防和研究中心（CEPROS）的研究人员之间建立一个合作研究项目。家长赠款是减少青少年物质使用的筛查和简要建议（1 R 01 DA 018848），由NIDA根据RFA-DA-04-006，初级保健环境中的青少年筛查和干预提供资金。母研究是一项在初级保健研究网络内进行的综合预防/简要建议干预的有效性试验。本研究采用非同期对照组设计，以测试的效果，提供即时反馈给青少年和初级保健提供者列出的建议子弹，具体到青少年的药物参与水平的提示表的计算机化筛选程序。将在年度油井维护访视时以及3个月和12个月后进行测量。结果将通过检查非使用者之间物质使用开始率的组间差异和使用者之间物质使用停止的差异进行评估。这一竞争性补充申请将在大布拉格地区增加9个初级保健实践。拟议的项目包括翻译/回翻译的计算机化的筛选程序和其他学习材料到捷克，CRAFFT屏幕捷克青年之间的验证研究，和翻译的筛选和简短的建议干预的对照试验使用的方法，平行的母研究。美国方面的好处将是（1）与捷克共和国的研究人员建立研究合作，（2）确定CRAFFT筛查在英语以外的语言中的有效性，（3）增加父母研究的力量，（4）了解筛查/简短建议中的文化差异，以及（5）为未来青少年药物滥用的跨文化研究做准备。对捷克方面来说，好处将是（1）与美国的研究人员建立研究合作，(2)验证一种新的青少年药物滥用的简易筛查测试，该测试可用于儿科初级保健，（3）测试一种新的儿科办公室筛查方法和药物使用的简要建议，（4）了解筛查/简要建议中的文化差异，以及（5）为未来青少年药物使用的跨文化研究做准备。

DESCRIPTION (provided by applicant): This competing supplement application is submitted to NIDA in response to PAS-03-023, International Research Collaboration on Drug Addiction. It will establish a collaborative research project between investigators from the Center for Adolescent Substance Abuse Research (CeASAR) at Harvard Medical School/Children's Hospital Boston and the Center for the Evaluation, Prevention, and Research of Substance Abuse (CEPROS) in the Czech Republic. The parent grant is Screening and Brief Advice to Reduce Teen Substance Use (1 R01 DA018848), which was funded by NIDA under RFA-DA-04-006, Screening and Intervention for Youth in Primary Care Settings. The parent study is an efficacy trial of a comprehensive prevention/brief advice intervention within a primary care research network. The study uses a noncontemporaneous control group design to test the effect of computerized screening program that provides immediate feedback to the adolescent and a prompt sheet for primary care providers listing advice bullets that are specific to the adolescent's level of drug involvement. Measurements will occur at the annual well care visit, and 3-months and 12-months later. Outcome will be assessed by examining between-groups differences in rates of substance use initiation among non-users, and differences in substance use cessation among users. This competing supplement application will add nine primary care practices in the Greater Prague area. The proposed project includes translation/back translation of the computerized screening program and other study materials into Czech, a validation study of the CRAFFT screen among Czech youth, and a controlled trial of the translated screening and brief advice intervention using methods that parallel those of the parent study. The benefits for the U.S. side will be to (1) build a research collaboration with investigators from the Czech Republic, (2) determine the validity of the CRAFFT screen in a language other than English, (3) increase power of the parent study, (4) gain an understanding of cultural variations in screening/brief advice, and (5) prepare for future cross-cultural studies of adolescent substance abuse. For the Czech side, the benefits will be (1) build a research collaboration with investigators from the U.S., (2) validate a new brief screening test for adolescent substance abuse that is practical for use in pediatric primary care, (3) test a new method of pediatric office screening and brief advice for drug use, (4) gain an understanding of cultural variations in screening/brief advice, and (5) prepare for future cross-cultural studies of adolescent substance use.