Validation of an Integrated Heart Rate/Activity Monitor

描述(由申请者提供)：该计划公告的一个主要目标是“支持通过改进的仪器、技术或统计/分析技术改进体力活动测量的研究”，以供“普通和多样化的人群”使用。根据这项探索性/开发性R21拨款申请提出的工作将涉及对新的体力活动监测器(PAM)的验证，该监测器最近由弗吉尼亚大学和巴伦联合公司共同开发。 PAM设备的新功能包括：(1)能够在单个、谨慎、低调的设备中同时收集惯性传感器和心率测量数据；以及(2)测量佩戴者身体重心(CM)的六个自由度(6-DOF)体轴加速度，这使得能够完全区分他们的CM在三维空间中的平移和旋转运动。这一能力转化为比其他商业活动记录仪更准确的活动能量支出估计。PAM系统还可以准确跟踪体力活动的时间、频率和强度。原始数据和处理后的数据都可以存储在PAM系统存储器中，以便随后离线上传到PC或个人数字助理(PDA)，或者通过蓝牙无线通信实时在线上传。 拟议的第一年工作的重点将是在一项对90名健康成年人的回顾研究中，对照代谢测量系统验证PAM能量支出估计的准确性和在不同活动强度水平下花费的时间。PAM系统的精确度(即仪器间和仪器内的可靠性)也将在第一年的工作中进行评估。拟议的第2年工作将涉及在类似受试者群体中对照代谢测量系统对PAM系统进行前瞻性验证，并将PAM估计数与其他适合现场使用的“专业级”活动监测仪的估计数进行比较。测试对象的体力活动范围从模拟日常生活活动到“最大有氧运动”。 PAM系统有很强的潜力影响缺乏运动对健康的不利影响，如心血管疾病、肥胖症和2型糖尿病。PAM系统还将在睡眠研究、步态研究、疼痛管理、老年稳定性评估和跌倒监测以及ADHD诊断等方面发挥作用。

DESCRIPTION (provided by applicant): A principle objective of the Program Announcement to which this grant proposal is responsive is to "support research to improve physical activity measurement through improved instruments, technologies, or statistical/analytic techniques" for use in "general and diverse populations." The work proposed under this exploratory/developmental R21 grant application will involve the validation of a new Physical Activity Monitor (PAM) that was recently developed as a collaborative effort by the University of Virginia and Barron Associates, Inc. Novel features of the PAM device include: (1) the ability to collect inertial sensor and heart rate measurement data simultaneously in a single, discreet, low-profile device; and (2) measurement of the six degree-of-freedom (6-DOF) body-axes accelerations of the wearer's center of mass (CM), which allows complete discrimination of the translational and rotational motions of their CM in three-dimensional space. This capability translates into more accurate activity energy expenditure estimates than is possible with other commercial actigraphs. The PAM system also enables accurate tracking of the timing, frequency, and intensity of physical activity. Both raw and processed data can be stored in PAM system memory for subsequent off-line uploading to a PC or personal digital assistant (PDA), or alternatively uploaded on-line in real time, via Bluetooth wireless communications. Focus of the proposed Year 1 effort will be to validate the accuracy of the PAM energy expenditure estimates and time spent at different activity intensity levels against a metabolic measurement system in a retrospective study of 90 healthy adults. Precision of the PAM system (i.e., inter- and intra-instrument reliability) will also be assessed in the Year 1 effort. The proposed Year 2 effort will involve the prospective validation of the PAM system against the metabolic measurement system in a similar subject population, and comparison of PAM estimates with that of other "professional-grade" activity monitors that are suitable for field use. Physical activities on which subjects will be tested range from simulated activities of daily living, to "naximal aerobic effort. The PAM system has strong potential to impact adverse health effects of physical inactivity, such as cardiovascular disease, obesity and type 2 diabetes. The PAM system will also be of benefit in sleep studies gait studies, pain management, geriatric stability assessment and fall monitoring, and diagnosis of ADHD, to name lust a few applications.