Nephrology and Hypertension Training Grant

超出所提供的空间。这是一份关于肾内科和高血压学科博士后研究培养计划的建议。目的是为医生和科学家准备在肾脏和高血压疾病以及正常和异常肾脏功能或血压调节的基础生物学方面进行独立调查。我们强调将尖端的基础研究技术应用于肾脏和高血压疾病的健康相关问题，包括血压和容量稳态的肾脏机制、受体调节、血管生理学、药理学和血管生成、细胞内信号传导、氧化应激、性别和妊娠对血管功能的影响、分子遗传学和肾脏血管活性因子之间的相互作用。候选人必须拥有医学博士或博士学位。医生将完成内科或儿科的临床培训，大多数医生将接受肾内科的临床专科培训。研究培训计划为期2年，期间患者护理活动将受到严格限制。候选人将由全体教员根据既定的研究和学术肾脏病学的职业目标、面试、推荐信和过去的表现来选择。候选人的进度将由项目主任和联合主任、个别教员导师评估，由培训教员审查，并审查正式报告和书面进度报告。所有的培训将在乔治城大学医学中心进行，在一个由医学、儿科、药理学、生理学和分子遗传学部门的培训教师组成的具有凝聚力和高度协作的实验室中进行。核心教师是美国国立卫生研究院项目拨款的Pi，因此承担由核心设施支持的研究。培训和支持人员来自基础和临床科室。主要教员是新成立的心血管肾脏研究所的成员。这提供了一个有凝聚力和协作的研究环境。为了利用这些特殊资源，并在此资助计划前5年的成功基础上再接再发展，我们建议将受训人数从4人扩大到6人。其目的是培养博士后科学家，除了医生，在学术肾脏病和高血压项目的职业生涯。网站性能 ======================================== 节结束 ===========================================

EXCEED THE SPACE PROVIDED. This is a proposal for a research training program for post-doctoral trainees in Nephrolbgy and Hypertension. The goal is to prepare physicians and scientists to undertake independent investigation in renal and hypertensive disorders and in the basic biology which underlies normal and aberrant kidney function or blood pressure regulation. We emphasize application of cutting edge basic research techniques to health related problems of renal and hypertensive disease that include studies of renal mechanisms of blood pressure and volume homeostasis, receptor regulation, vascular physiology, pharmacology and angiogenesis, intracellular signaling, oxidative stress, effects of gender and pregnancy on vascular function, molecular genetics and interactions between vasoactive factors in the kidney. Candidates will have the MD and/or PhD. Physicians will have completed clinical training in either internal medicine or pediatrics and most will undertake clinical subspecialty training in nephrology. The research training program will be for 2 years, during which patient care activities will be strictly limited. Candidates will be selected by the entire faculty based upon stated career goals in research and academic nephrology, interviews, letters of recommendation, and past performance. Progress of candidates will be assessed by the program director and co-director, individual faculty preceptors, review by the training faculty and review of formal presentations and written progress reports. All training will be carried out at Georgetown University Medical Center, in the laboratories of a cohesive and highly collaborative group of training faculty drawn from the Department of Medicine, Pediatrics, Pharmacology, Physiology, and Molecular Genetics. The core faculty are the Pi's of an NIH Program Project Grant and thereby undertake research supported by core facilities. The training and support faculty are drawn from basic and clinical departments. The key faculty are members of the newly formed Cardiovascular Kidney Institute. This provides a cohesive and collaborative research environment. To utilize these special resources and to build on the successes of the first 5 years of this grant program, we propose to expand the number of trainees from 4 to 6. The aim is to train post-doctoral scientists, in additional to physicians, for a career in academic nephrology and hypertension program. PERFORMANCE SITE ========================================Section End===========================================