Epidemiology, Clinical Trials, and Outcomes Research

描述(由申请人提供)： 来自国家卫生研究院和医学研究所的报告建议加强医生在临床研究方法方面的培训计划，以将基础科学的进步转化为健康的改善。这一修改后的申请是为了更新五年前在塔夫茨-新英格兰医学中心和塔夫茨大学医学院肾脏病学部建立的“流行病学、临床试验和结果研究”的培训计划。安德鲁·S·利维医学博士和马克·萨纳克医学博士分别是项目主任和副项目主任。拟议的培训计划的独特之处在于，它将肾病学家的培训与尖端临床研究的杰出记录以及流行病学、生物统计学和卫生服务研究的世界领先者的培训结合在一起。教师监督与内部和外部顾问的监督相辅相成，这些顾问由来自学术界、政府和商界的高级调查人员和高管组成。 具体目标如下：1)塔夫茨大学萨克勒生物医学研究生院临床研究研究生项目硕士学位的教学培训课程。2)独立研究--一项以假设为基础的研究项目，由一名肾病学家导师和一支在其他学科具有专业知识的教员组成的研究团队监督。肾病学教师和他们的合作者拥有数据库和正在进行的研究，可以作为受训者研究项目的主题。3)陈述方面的培训--参加旨在提高受训者口头和书面陈述的会议和研讨会。肾病学家导师确保将课程的所有方面与受训者的研究项目相结合。 在最初的五年里，该计划已经演变成专注于慢性肾脏疾病，这是一个影响美国2000多万成年人的公共健康问题。所有18个核准的实习生职位都已填补。另有41个受训人员职位由其他来源提供支助。在完成项目的20名学员中，13人留在了学术医学领域，5人在工业或政府部门，2人进入了私人执业。到目前为止，已收到50份2005年的申请。要求在今后五年内每年更新四个培训职位，每年增加一个职位

DESCRIPTION (provided by applicant): Reports from the National Institutes of Health and Institute of Medicine recommend strengthening training programs for physicians in the methods of clinical research to translate advances in basic science to improvements in health. This amended application is to renew the training program in "Epidemiology, Clinical Trials and Outcomes Research" established five years ago within the Division of Nephrology at Tufts-New England Medical Center and Tufts University School of Medicine. Andrew S. Levey, MD and Mark Sarnak, MD are the Program Director and Associate Program Director, respectively. The proposed training program is unique in that it combines training by nephrologists with outstanding records in cutting-edge clinical research and by world leaders in epidemiology, biostatistics and health services research. Faculty supervision is complemented by oversight by internal and external advisors, consisting of senior investigators and executives from academia, government and business. The specific aims are as follows: 1) Didactic Training - course work in fulfillment of the MS degree in the Graduate Program in Clinical Research at the Sackler School of Graduate Biomedical Sciences at Tufts University. 2) Independent Study - an hypothesis-based research project supervised by a nephrologist mentor and a research team of faculty with expertise in other disciplines. Nephrology faculty and their collaborators have databases and ongoing studies that can serve as the subject of the trainees' research projects. 3) Training in Presentation - participation in conferences and seminars designed to improve trainees' oral and written presentations. Integration of all aspects of the curriculum with trainees' research projects is ensured by the nephrologist mentors. During the first five years, the Program has evolved to focus on chronic kidney disease, a public health problem affecting more than 20 million adults in the US. All 18 approved trainee positions have been filled. An additional 41 trainee positions have been supported by other sources. Of the 20 trainees who have completed the program, 13 have remained in academic medicine, 5 are in industry or government, and 2 have entered private practice. To date, 50 applications have been received for 2005. Renewal of four training positions per year and addition of one position per year are requested for the next five years