How should we analyse, synthesize, and interpret evidence from interrupted time series studies? Making the best use of available evidence

中断时间序列(ITS)研究经常被用来评估政策干预是否成功。这些研究的结果通常被整理成系统的评估，用于为临床医生、消费者和政策制定者的医疗决策提供信息。目前尚不清楚作为其研究结果基础的统计方法的表现如何。该提案将对统计方法进行评价，并就如何分析和解释其研究提供指导。

Interrupted time series (ITS) studies are frequently used to evaluate whether policy interventions are successful. The findings from these studies are often collated into systematic reviews, which are used to inform healthcare decisions by clinicians, consumers and policy makers. It is not known how the statistical methods, which underpin the findings from ITS studies, perform. This proposal will evaluate the statistical methods and provide guidance on how to analyse and interpret ITS studies.