Long Stroke Wavefront Correctors for Retinal Imaging

该提案描述了一项计划，以证明一种设备的可行性，该设备将实现常规的高分辨率，高对比度视网膜成像-用于眼科自适应光学系统的长行程微加工变形镜。一个主要目标将是开发长行程MEMS致动器阵列，适合用作可变形反射镜的平台，这将允许至少90%的人口通过散瞳进行衍射限制的视网膜成像。成功的长行程致动器原型将用于在第二阶段开发MEMS-DM。第二个目标将是生产一种紧凑的、可调节的波前校正模块，该模块结合了MEMS-DM、控制电子器件、扩展DM的有效波前行程的新型光学倍增器以及允许系统跨平台功能的软件驱动器。 该模块将为MEMS-DM插入眼科AO系统提供便携式平台，并将促进DM在视网膜成像平台中的模块化插入。更高分辨率的视网膜成像系统将允许早期诊断和治疗视网膜疾病，包括糖尿病视网膜病变和年龄相关性黄斑变性。

This proposal describes a plan to demonstrate feasibility of a device that will enable routine high-resolution, high-contrast retinal imaging - a long-stroke micromachined deformable mirror for use in ophthalmic adaptive optics systems. A principal goal will be to develop long stroke MEMS-actuator arrays suitable for use as a platform for deformable mirrors that will permit diffraction-limited retinal imaging through dilated pupils in at least 90% of the human population. Successful long-stroke actuator prototypes will be used to develop a MEMS-DM in Phase II. A second goal will be to produce a compact, adjustable wavefront correction module that combines MEMS-DMs, control electronics, a novel optical doubler that extends the DM's effective wavefront stroke, and software drivers allowing cross-platform functionality to the system. This module will provide a portable platform for insertion of MEMS-DMs into ophthalmic AO systems, and will facilitate modular insertion of the DM in retinal imaging platforms. Higher resolution retinal imaging systems will permit earlier diagnosis and treatment of retinal diseases, including diabetic retinopathy and age-related macular degeneration.