A Novel Liquid Oxygen Recharger for Home Oxygen Therapy

描述（由申请人提供）：本研究项目的具体目标是开发和过渡一种低成本的液氧（LOX）生成系统，以支持使用家庭氧疗（HOT）的非卧床患者。目前在美国，每年在HOT上的支出接近20亿美元。由于婴儿潮一代的老龄化，这些支出将在未来10年急剧增加。由于人口统计学、患者和临床医生的偏好以及HOT作为治疗方案的普遍成功，预计基于LOX的HOT系统的使用将继续增加。基于LOX的系统的主要缺点是高操作成本，因为这些系统的储存容器必须频繁地用LOX再填充。Creare的创新是一个小型液氧发生系统（MLGS）。这种新型装置是一种小型、低功耗、低成本的系统，可以从大气中产生液氧。创新的基础是我们为军事开发的液氧系统的小型化。我们的新系统将直接补充便携式液氧装置，消除了对储存库和液氧再供应基础设施的需要。因此，我们的创新将大大降低基于LOX的HOT的成本，同时提高便利性，安全性和合规性。

DESCRIPTION (provided by applicant): The specific aim of this research program is to develop and transition a low-cost, liquid oxygen (LOX) generation system to support ambulatory patients using Home Oxygen Therapy (HOT). Currently in the United States, yearly expenditures on HOT are nearly two billion dollars. These expenditures will increase dramatically over the next 10 years due to the aging baby-boomer generation. The increase in use of LOX-based HOT systems is expected to continue due to demographics, patient and clinician preferences, and the general success of HOT as a treatment regimen. The primary drawback of LOX-based systems is the high-operational cost, because the storage reservoir for these systems must be refilled with LOX frequently. Creare's innovation is a Miniaturized LOX Generation System (MLGS). This novel device is a small, low-power, low-cost system that generates liquid oxygen from atmospheric air. The basis of the innovation is the miniaturization of the liquid oxygen systems we have developed for the military. Our novel system will directly refill the portable LOX unit, eliminating the need for the storage reservoir, and the LOX re-supply infrastructure. Thus, our innovation will substantially reduce the cost of LOX-based HOT, while improving convenience, safety, and compliance.