ADOLESCENT MEDICINE TRIALS UNIT AT CHOP

费城儿童医院（CHOP）拟议的青少年医学试验单位（AMTU）将成为艾滋病毒/艾滋病干预青少年医学试验网络的一个站点。在CHOP现场，至少有75名HIV阳性和125名年龄在12至24岁之间的HIV阴性干预研究参与者将被确定并维持为未来研究的潜在人群。试验股工作人员将负责筛选所有参与者，并为当地方案开发和维护中央管理数据库。CHOP AMTU的工作人员将为当地项目的协议制定做出贡献。中国农业大学联合会的工作人员将为国家工作的协议制定作出贡献，并将完成中国农业大学联合会场址所需的所有数据收集工作。主要研究者和研究协调员将充分参与网络。妇联在CHOP的活动的中心部分将是向感染艾滋病毒的青年伸出援手。正在进行的教育、咨询和测试工作，以及合作转诊站点的活跃网络的维护，将是确保获得所需数量的潜在研究参与者的关键因素。CHOP已经开展的社区教育工作和一个针对感染艾滋病毒的青年的强有力的临床护理方案将支持该协会成为一个充分参与国家努力的机构。CHOP青少年医学部繁忙的青少年护理中心和社区青少年护理外展项目将参与该项目，作为确定适当的艾滋病毒阴性青年进行干预试验的手段。来中心的人将被告知该网络的活动，并在制定协议的同时培养他们的参与。费城儿童医院（Children’s Hospital of Philadelphia）有一个完善的项目来支持临床研究工作和临床试验，比如那些即将被该网络锁定的项目。美国国立卫生研究院支持的儿科普通临床研究中心、机构支持的临床试验单位、儿科药理学研究单位和约瑟夫·塞斯研究所的技术和结构支持都将提供给CHOP的AMTU。

The proposed Adolescent Medicine Trails Unit (AMTU) at The Children's Hospital of Philadelphia (CHOP) will be one site for the Adolescent Medicine Trails Network for HIV/AIDS Interventions. At the CHOP site, at least 75 HIV-positive and 125 HIV -negative intervention study participants between the ages of 12 to 24 years will be identified and maintained as a potential population for future studies. The Trail Unit staff will be responsible for screening all participates and in the development and maintenance of the central managerial database for the local program. Staff of the CHOP AMTU will contribute to protocol development for the local program. Staff of the CHOP AMTU will contribute to protocol development for the national effort and will complete all data collection efforts required of an AMTU site. The Principle Investigator and Study Coordinator will participate fully in the Network. A central part of the activities of the activities of the AMTU at CHOP will be outreach to HIV-infected youth. Ongoing education, counseling, and testing efforts, as well as the maintenance of an active network of collaborating referral sites, will be critical elements in assuring the availability of the required number of potential research participants. Community education efforts already in existence at CHOP and a strong clinical care program for HIV-infected youth will support the AMTU's ability to be a fully participating site in the national effort. The busy Adolescent Care Center and community adolescent care outreach programs of the Division of Adolescent Medicine at CHOP will be involved in the project as means of identifying appropriate HIV- negative youth for intervention trials. Those coming to the Center will be told about the activities of the Network and their participation will be cultivated while protocols are developed. The Children's Hospital of Philadelphia has a well-developed program to support clinical research efforts and clinical trails like those to be latched by the network. Technical and structural support from the NIH-supported Pediatric General Clinical Research Center, the institutionally-supported clinical trails unit, the pediatric pharmacology research unit, and the Joseph Sakes Research Institute will all be availably to the AMTU at CHOP.