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INTERNATIONAL TRAINING IN AIDS/TB PREVENTION RESEARCH

INTERNATIONAL TRAINING IN AIDS/TB PREVENTION RESEARCH
艾滋病/结核病预防研究国际培训
批准号:
6779131
负责人:
Vinayaka R. Prasad
金额:
$25.47万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-09-30 至 2006-06-30

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项目成果

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中文摘要
翻译
这个在阿尔伯特·爱因斯坦医学院(AECOM)开展的艾滋病/结核病预防研究国际培训项目主要侧重于印度,并包括一个针对厄立特里亚的小项目。为了实现我们在这些国家进行能力建设的目标,我们的目标是培训印度和厄立特里亚的科学家进行关键的生物医学研究、行为/流行病学研究以及临床研究。短期培训将涉及在纽约市举办的专门讲习班以及将与国际疫苗倡议等国际机构在印度进行疫苗试验的地点进行协调的国内地点。中期培训将包括其研究导师的研究生,他们将进行合作研究,以获得以下领域的培训,包括但不限于:HIV-1印度分支的特征;艾滋病病毒耐药性测定;利用小动物模型研究营养不良对HIV感染的影响;接种v3环肽疫苗以预防母胎传播,使用快速、廉价的结核分枝杆菌耐药菌株检测系统,以及开发诊断抗体和其他针对印度新型隐球菌亚型的血清诊断和分子工具。此外,提供临床研究培训硕士学位和艾滋病/结核病研究博士后研究培训计划。此外,该项目还将帮助开发低成本的艾滋病毒/艾滋病技术,协调建立印度重新定位的基本艾滋病毒亚型c特异性试剂,并计划帮助前受训人员在回国后独立建立独立的艾滋病研究项目,并在能力建设工作中与他们互动。
英文摘要
This international training program in AIDS/TB prevention research at the Albert Einstein College of medicine (AECOM) focuses mainly on India and includes a small program for Eritrea. Towards our goal of capacity building in these countries, we aim to train Indian and Eritrean scientists in critical biomedical research, behavioral/epidemiological studies, as well as clinical research. Short-term training will involved specialized workshops in New York City was well as in-country sites that are going to be coordinated with sites in India where vaccine trials are going to conducted by international agencies such as IAVI. Medium-term training will include both graduate students of their Research Mentors who will perform collaborative research for acquiring training in the areas including but not limited to: characterization of the Indian clade of HIV-1; measurement of drug-resistance in HIV; use of small animal models to study the effect of malnutrition on HIV infection; administration of V3-loop peptide vaccine to prevent materno-fetal transmission, the use of a rapid, inexpensive detection system for drug- resistant strains of Mycobacterium tuberculosis, and the development of diagnostic antibodies and other serodiagnostic and molecular tools specific to the Indian subtype of Cryptococcus neoformans. Furthermore, a Master's degree in Clinical Research Training Program and a Post- doctoral Research Training Program are offered in AIDS/TB research. Furthermore, the program will help develop low-cost HIV/AIDS technologies, mediate the creation of an Indian reposition of essential, HIV clade C-specific reagents and plans to help former trainees independent establish independent AIDS research programs upon their return to their home countries and to interact with them in this capacity- building effort.
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CCL2-CCR2b signaling in HIV-1 fitness and disease; Role of host genetic polymorphisms
CCL2-CCR2b signaling in HIV-1 fitness and disease; Role of host genetic polymorphisms
CCL2-CCR2b signaling in HIV-1 fitness and disease; Role of host genetic polymorphisms
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