Network Chair for the Pacific Northwest DPBRN

描述（由申请人提供）：我们建议建立太平洋西北牙科实践为基础的研究网络（PNW/DPBRN），并在此申请中创建网络主席办公室。这个网络椅子申请是作为华盛顿大学和俄勒冈州健康与科学大学牙科学院之间的合作努力提交的。主要研究者是Timothy A。DeRouen博士，华盛顿大学研究和学术事务执行副院长，生物统计学和牙科公共卫生科学教授，因此华盛顿大学是申请机构。Co-P.I.是杰克·费拉卡尼博士OHSU修复牙科学教授兼主席，OHSU是分包机构。主要的临床合作研究者是乔尔贝格，DDS，MS，华盛顿大学和托马斯希尔顿，DMD，MS的OHSU。PNW网络被提议用于华盛顿、俄勒冈州、爱达荷州、蒙大拿州和犹他州这五个州的区域。这一拟议团队努力的成功可能性取决于团队在关键领域的相关经验，包括DeRouen博士作为P.I.的经验。在NIDCR资助的多中心临床试验和在临床牙科研究中开发模型培训计划方面的经验，贝格博士在行业赞助的临床试验中招募和监督临床医生的经验，以及Ferracane博士和希尔顿博士在俄勒冈州和西南华盛顿开发基于实践的口腔健康研究网络的经验。一个重要的合作者是三角洲牙科，数据分析中心，通过该中心可以获得基于三角洲牙科保险索赔的试点和观察性研究的数据。提议建立一个组织结构，共同监督这项行动，其中包括使用分布在这一广大地理区域的五名区域协调员。提出了一个积极的网络从业人员招聘战略，包括与国家牙科协会，牙科校友会，特别是与当地的牙科学习俱乐部。将为参与者提供一个教育计划，该计划是基于非常成功的临床牙科研究方法暑期研究所。除了RFA授权的执行委员会、方案审查委员会和DSMB外，还提议设立一个出版物委员会、一个牙科保险联络委员会和一个外部咨询委员会，以促进该网络的运作。该应用程序与一个应用程序配对，成为数据协调中心，该中心也来自华盛顿大学，由Brian Leroux博士负责。作为私家侦探和生物统计学核心的其他成员作为共同研究者。鉴于DeRouen博士以前开发生物统计核心的历史，网络主席和协调中心之间的密切合作和协调是有保证的。

DESCRIPTION (provided by applicant): We propose to establish the Pacific Northwest Dental Practice Based Research Network (PNW/DPBRN), and to create the Office of the Network Chair in this application. This Network Chair application is submitted as a collaborative effort between the University of Washington and Oregon Health and Science University Schools of Dentistry. Principal Investigator is Timothy A. DeRouen, Ph.D., Executive Associate Dean for Research and Academic Affairs and Professor of Biostatistics and Dental Public Health Sciences at UW, so the University of Washington is the applicant institution. Co-P.I. is Jack Ferracane, Ph.D., Professor and Chairman of Restorative Dentistry at OHSU, with OHSU as a subcontracting institution. Key clinical co-investigators are Joel Berg, DDS, MS, of UW and Thomas Hilton, DMD, MS of OHSU. The PNW network is proposed for the five state area of Washington, Oregon, Idaho, Montana, and Utah. The likelihood of success of this proposed team effort is predicated on the very relevant prior experience of the team in crucial areas, including Dr. DeRouen's experience as P.I. on an NIDCR-funded multicenter clinical trial and in developing model training programs jn clinical dental research, Dr. Berg's experience in recruiting and overseeing clinicians in industry-sponsored clinical trials, and the experience of Drs. Ferracane and Hilton in developing a Practice-based Research in Oral Health network of dentists in Oregon and Southwest Washington. An important collaborator is the Delta Dental,Data Analysis Center, through which data for pilot and observational studies based on Delta Dental insurance claims in the five state network region can be obtained. An organizational structure is proposed for shared oversight of the operation which includes the use of five regional coordinators spread across this large geographical region. An aggressive strategy of recruitment of Network practitioners is proposed that includes working with state dental associations, dental alumni associations, and especially with local dental study clubs. An educational program for participants will be offered that is based on the highly successful Summer Institute in Clinical Dental Research Methods. Besides the Executive and Protocol Review Committees and DSMB mandated by the RFA, also proposed to facilitate the operations of the Network are a Publications Committee, a Dental Insurance Liaison Committee, and an External Advisory Committee. This application is paired with one to become the Data Coordinating Center, also from the University of Washington, with Brian Leroux, Ph.D. as P.I. and other members of the Biometry Core as co-investigators. Given Dr. DeRouen's previous history in developing the Biometry Core, close collaboration and coordination between Network Chair and Coordinating Center is.assured.