Analysis of CIGTS Visual Field Data

描述（由申请人提供）：CIGTS数据库和患者文件包含对607例新诊断、既往未经治疗的开角型青光眼（OAG）患者进行9年随访收集的Humphrey 24-2视野（VF）信息的广泛收集。这些患者被随机分配到初始药物或手术治疗组。该VF资源代表了大量关于VF变化的纵向随访数据。在访问先前输入的数据并输入来自所有收集的Humphrey 24-2视野的进一步数据之后，将追求以下三个目标：1.确定眼内压（IOP）控制与最佳VF结局相关的方式。 2.评估非裔美国人和白人中进行性VF丧失的风险。 3.确定除IOP控制和种族以外的因素对进行性VF丧失的相对影响。 说明年龄、性别、家族史、合并症、吸烟、饮酒、屈光不正和基线VF损伤。

DESCRIPTION (provided by applicant): The CIGTS database and patient files contain an extensive collection of Humphrey 24-2 visual field (VF) information gathered over nine years of follow-up on 607 patients with newly-diagnosed, previously un-treated open-angle glaucoma (OAG). These patients were randomized to initial medical or surgical treatment. This VF resource represents a wealth of longitudinal follow-up data on VF change. The following three aims will be pursued after accessing previously entered data and entering further data from all collected Humphrey 24-2 visual fields: 1. Determine the ways in which intraocular pressure (IOP) control is associated with the best VF outcomes. 2. Evaluate the risk of progressive VF loss among African Americans and whites. 3. Determine the relative impact of factors other than IOP control and race on progressive VF loss. Address age, sex, family history, comorbidities, smoking, alcohol ingestion, refractive error, and baseline VF damage.