Towards the Rational Design and Scale-up of Green Photoreactors

化学反应的光化学活化有望补充热活化过程的合成途径，这可以更加节能和可持续。此外，它们可以是更原子经济的，并减少所需的合成步骤数（步骤经济性），并且在许多情况下c提供优于热活化方法的上级选择性。然而，尽管光化学的研究已经有150多年的历史，但很少有光化学过程在工业规模上使用。本研究项目将通过阐明面向目标的光反应器设计的基本概念来解决克服这一障碍的关键挑战。为此，我们将使用光反应器的空间分辨光子强度的尖端建模，以及使用先进的表征方法进行实验验证，包括停止流动和周期性操作，再加上实验设计和自动化测试。在建模能力和已形成的理解的基础上，该项目的目标是使用可扩展反应堆概念的合理设计，以商业上可用的反应堆解决方案为基础进行建造、测试和基准测试。

Photochemical activation of chemical reactions promises complementary synthetic pathways to thermally activated processes, which can be much more energy-efficient, and sustainable. Moreover, they can be more atom economic and reduce the required number of synthetic steps (step economy) and in many cases c offers superior selectivity over thermally activated processes. Nevertheless, and despite the fact that there has been research on photochemistry for more than 150 years, few photochemical processes are used on an industrial scale. This research project will tackle the key challenges to overcoming this barrier by elucidating the fundamental concepts for target-oriented photoreactor design. To this end we will use cutting-edge modelling of photoreactors with respect to spatially resolved photon intensity, as well as experimental validation using advanced methods of characterization including stopped flow and periodic operation coupled with design of experiments and automated testing. Building on the modelling capabilities and the developed understanding, the project will aim to use the rational design of a scalable reactor concept to construct, test and benchmark against commercially available reactor solutions.