Guiding Adaptive Behaviour by Memory of Different Timescales and the Underlying Neural Mechanisms

我们的大脑在将传入的感觉信号与过去的经验进行匹配方面非常出色，这会引导我们选择性地注意，并允许我们根据预测和预期做出适应性和动态的行为。不同时间尺度的记忆参与引导知觉和执行，但到目前为止，我们仍然缺乏对远程长期记忆(LTM)和当前工作记忆(WM)如何共同作用于体验的清楚理解，也不知道潜在的神经机制。这个项目将设计新的行为任务，结合神经成像技术(如功能磁共振成像、脑磁图/脑电)和计算建模，以阐明记忆的前瞻性是如何以多时间尺度和交互方式运作的。

Our brain is extraordinary at matching incoming sensory signals to past experiences, which guides selective attention and allows us to behave adaptively and dynamically based on predictions and expectations. Memories of different timescales are involved in guiding perception and performance, but so far we still lack a clear understanding of how remote long-term memories (LTM) and current working memories (WM) work together to "premember" experience, and neither do we know the underlying neural mechanisms. This project will design novel behavioural tasks, in combination with neuroimaging techniques (e.g. fMRI, MEG/EEG) and computational modelling, to elucidate how the prospective nature of memory operates in a multi-timescale and interactive way.