Understanding the role of axillary corynebacteria in thioalcohol-mediated odour production

人体体味的产生是腋下（腋下）的共生细菌对大汗腺分泌的无味分泌物进行作用的结果。之前在联合利华实验室的研究发现，人型葡萄球菌是硫乙醇BO成分的主要生产者。然而，在相同的生态位中，有一些细菌被认为可以产生相同的气味，包括不同的棒状杆菌。该项目将通过继续研究参与该过程的关键转运体和酶的结构和生化特性，研究这些不同细菌在硫醇生产中的作用，并开始梳理我们在该过程中腋窝微生物群不同组分之间的潜在协同作用。

The production of body odour in humans is the result of the activity of commensal bacteria in the underarm (axilla) working on odourless secretions from our apocrine glands. Previous work in the lab with Unilever led to the discovery of Staphylococcus hominis as being a key producer of the thioalcohol BO component. However, there are bacteria in the same niche that have been proposed to create the same odours including different Corynebacteria. This project will examine the role of these different bacteria in thioalcohol production by continuing to investigate the structural and biochemical properties of key transporters and enzymes involved in the process and start to tease our potential synergies between different components of the axilla microbiota in this process.