Interhemispheric Research/Training in Infectious Disease

描述（由申请人提供）：这项国际培训补助金的总体目标是培训来自巴西的生物医学科学家和卫生专业人员进行传染病研究，以提高他们防治巴西难治性传染病的能力。拟议的培训计划是巴西和美国阿尔伯特·爱因斯坦医学院（AECOM）研究人员之间长期建立的研究合作的自然延伸。这项申请的目的是利用最先进的科学知识和技术技能，以加强预防、治疗和控制在巴西造成大量发病率和死亡率的主要传染病的方案。我们将重点关注巴西特有的感染，巴西科学家和机构与阿尔伯特·爱因斯坦医学院（AECOM）的科学家之间存在合作互动。巴西的参与机构是里约热内卢联邦大学和奥斯瓦尔多·克鲁兹基金会（FIOCRUZ）。我们重点关注的疾病包括：由克氏锥虫寄生虫引起的恰加斯病，它是巴西成年人心脏病的主要病因；麻风病、真菌病和寄生虫病，包括弓形虫病和疟疾。拟议的培训计划包括教学和实验部分，以及（道德）正式课程。参与者包括研究生（短期参与者），博士后和青年教师（长期参与者）。一些参与者将有资格获得临床研究和培训硕士学位。因此，这项培训建议在利用东道国机构（AECOM）已建立的研究合作和教育方案方面具有创新性，并将对在巴西建立相关传染病的可持续研究能力的长期目标作出重大贡献。

DESCRIPTION (provided by applicant): The overarching objective of this International Training Grant is the training of biomedical scientists and health professionals from Brazil in infectious diseases research in order to enhance their capabilities to combat the intractable infectious diseases endemic in Brazil. The proposed training program is the natural extension of long-established research collaborations between investigators in Brazil and investigators in the U.S. at the Albert Einstein College of Medicine (AECOM). The aim of this application is to harness state-of-the-art scientific knowledge and technical skills in order to augment programs to prevent, treat and control the major infectious diseases causing significant morbidity and mortality in Brazil. We will focus on those infections unique to Brazil and for which there are existing collaborative interactions between the Brazilian scientists and institutions and the scientists at The Albert Einstein College of Medicine (AECOM). The participating institutions in Brazil are The Federal University of Rio de Janeiro and the Foundation Oswaldo Cruz (FIOCRUZ). The diseases on which we have focused include Chagas' disease, caused by the parasite Trypanosoma cruzi, a major cause of heart disease in adults in Brazil; leprosy, fungal diseases, and parasitic diseases including toxoplasmosis and malaria. The proposed training program includes both didactic and laboratory components, as well as a formal course in (ethics). Participants will include graduate students (short term participants), and postdoctoral fellows and young faculty (long-term participants). Some participants will be eligible for a Masters Degree in Clinical Research and Training. This training proposal is thus innovative in its use of the established research collaborations and education programs of the host institution (AECOM), and will contribute significantly to the long term goal of building sustainable research capacity in relevant infectious diseases in Brazil.