Albany Medical College (AMC) Research Laboratory Facility Expansion and Improveme

描述(由申请人提供)：奥尔巴尼医学院(AMC)是一所私立医学和研究生教育机构，独立于纽约州立大学(SUNY)或任何其他大学系统。基础和转化性生物医学研究目前仅限于最初建于1961年和1970年的两座毗邻建筑。研究空间和基础设施(80,703个NSF)高度划分，几乎100%投入使用，其中只有20%在过去10年内进行了翻新。陈旧、僵化的研究基础设施，加上缺乏空置的实验室空间，直接限制了我们满足57名当前和/或即将获得NIH资助的研究人员日益增长的需求的能力，并严重限制了我们招募未来教员参与研究项目的能力。2008年，奥尔巴尼医学中心承诺投资500万美元，建造一座与目前的学院研究大楼相邻的壳体结构。该结构(学院研究设施)正在建设中，旨在包括未来垂直扩展的最多三层额外空间。然而，由于最近的经济衰退加剧了机构的财政限制，目前没有关于增加新的研究实验室空间的计划或已承诺的资金。恢复法有限竞争：校外研究设施改善计划(C06)为奥尔巴尼医学院提供了一个独特的机会，通过在学院研究设施结构上增加两个完工的实验室楼层，为NIH资助的研究提供了一个独特的机会，从而产生了总共20,072个NSF的新的现代化、灵活设计的实验室和支持空间。每一层都将设计为开放式实验室，包括固定长凳和完全模块化的空间；用于细胞培养、显微镜、大型设备、玻璃清洗/干燥和高压灭菌器的支持室；寒冷/环境室；以及供人员使用的支持空间，包括教职员工/同事办公室、教职员工非正式会议室和正式会议室。该空间旨在根据不断变化的方案需求、内部和外部合作机会以及调查员资金，为空间分配提供效率和灵活性。拟议的实验室空间和固定设备将使AMC能够通过以下支持显著扩大其由NIH资助的研究能力：1)NIH现有资助项目的增长；2.)开发多个调查员协作项目；以及3.)招聘8-10名具有互补翻译研究项目的新教员。该项目通过以下方式满足《复兴法案》的总体目标：为建筑工人和工程师提供直接就业机会；为不断增长的NIH资助的实验室的学生、研究员和实验室工作人员提供新的培训和就业机会；以及建造符合LEED认证标准的新的高效实验室空间。

DESCRIPTION (provided by applicant): Albany Medical College (AMC) is a private medical and graduate education institution unaffiliated with the State University of New York (SUNY) or any other university system. Basic and translational biomedical research is currently confined to two adjoining buildings originally constructed in 1961 and 1970. Research space and infrastructure (80,703 NSF) is highly compartmentalized, nearly 100% committed, and only 20% of it has been renovated within the past 10 years. The aged, inflexible research infrastructure, combined with lack of vacant laboratory space, places immediate limitations on our ability to accommodate growing needs of 57 current and/or pending NIH-funded investigators, and severely limits our ability to recruit future faculty members with research programs. In 2008, Albany Medical Center committed $5 M to build a shell structure contiguous with the current College research buildings. This structure (College Research Facility) is under construction and was designed to include capacity for up to three additional floors of future vertical expansion. However, due to institutional financial constraints exacerbated by the recent economic downturn, there are no current plans in place or committed funds for adding new research laboratory space. The Recovery Act Limited Competition: Extramural Research Facilities Improvement Program (C06) provides a unique opportunity for Albany Medical College to expand its capacity for NIH-funded research by addition of two finished laboratory floors to the College Research Facility structure resulting in a total of 20,072 NSF of new modern, flexibly designed laboratory and support space. Each floor will be designed with open laboratories consisting of a combination of fixed benches and fully modular space; supporting rooms for cell culture, microscopy, large equipment, glass wash/dry and autoclave; cold/environmental rooms; and supporting space for personnel including faculty/fellow offices, faculty/staff informal meeting area, and a formal conference room. The space is designed to provide efficiency and flexibility for space assignments based on changing programmatic needs, internal and external collaborative opportunities, and investigator funding. The proposed laboratory space and fixed equipment will allow AMC to significantly expand its NIH-funded research capacity by supporting: 1.) growth of existing NIH-funded programs; 2.) development of multi- investigator collaborative projects; and 3.) recruitment of 8-10 new faculty members with complementary translational research programs. The project meets general goals of the Recovery Act by: providing immediate employment opportunities for construction workers and engineers; providing new training and employment opportunities for students, fellows and laboratory staff in growing NIH-funded laboratories; and by building new efficient laboratory space meeting LEED standards for certification.