2005 Chronobiology Gordon Research Conference

描述(由申请者提供)：第14届戈登时间生物学研究会议将在罗德岛州纽波特的萨尔维里贾纳大学举行，现申请部分资助。近年来，体内生物钟(生物钟)在调节和调节时间生理方面的重要性日益明显，因此，人们致力于分析昼夜节律过程的机制。人们认识到昼夜节律在人类健康和疾病中发挥的关键作用，再加上最近关于产生和调节昼夜节律系统的分子机制的里程碑式的发现，导致该领域的显著扩大。今天，时间生物学研究吸引了来自广泛学科的大量研究人员，包括分子遗传学、神经科学、光生物学、计算生物学和新陈代谢，以及睡眠医学、精神病学、肿瘤学和老年学。戈登时间生物学会议的目的是：(1)为讨论和确定迅速扩大的时间生物学领域的一般原则提供一个论坛。(2)促进时间生物学各分支学科的研究人员之间的互动，从而加强整个研究领域的一致性。(3)加强年轻和成熟研究人员之间的互动，从而保持高质量的时间生物学研究。(4)通过汇集来自许多不同研究小组和国家的科学家，促进国家和国际合作。(5)通过将使用模式生物的研究人员与研究昼夜节律研究的人类对象的研究人员聚集在一起，促进翻译研究。这次会议将汇集约150名科学家，包括来自不同国家、不同年龄段、不同性别的个人，并使用不同的研究模式，从而实现这些目标。我们将通过邀请个人和直接联系少数族裔大学(如莫尔豪斯学院)来鼓励少数群体的积极参与。该计划将侧重于关键研究领域的新的和正在出现的发展(见暂定计划)。按照非常成功的戈登会议形式，讲座将分9个上午和晚上进行，有充足的讨论时间。下午晚些时候的三次海报会议将允许参与者展示更多数据。特别注意实现性别平衡和吸收来自非常不同学科的专家，以实现对我们科学前沿的广泛了解和对未来机会的洞察。结果将对改善表现为睡眠、情感、认知、神经、代谢、内分泌和肿瘤疾病的功能障碍具有健康相关性。

DESCRIPTION (provided by applicant): Partial support is requested for the 14th Gordon Research Conference on Chronobiology, to be held at Salve Regina University, Newport, Rhode Island. In recent years, the significance of internal body clocks (circadian clocks) in regulating and adjusting temporal physiology has become increasingly clear and, as a consequence, much effort has been devoted to the analysis of the mechanisms underlying circadian processes. Recognition of the key role played by circadian rhythms in human health and disease, combined with recent landmark discoveries regarding the molecular mechanisms that both generate and regulate the circadian system, has led to a remarkable expansion of the field. Today, chronobiological research attracts a host of researchers from a broad range of disciplines, including molecular genetics, neuroscience, photobiology, computational biology and metabolism, as well as sleep medicine, psychiatry, oncology and gerontology. The aims of the Gordon Conference on Chronobiology are: (1) To provide a forum for discussion and for identifying general principles in the rapidly expanding field of Chronobiology. (2) To stimulate interactions among researchers working in the various sub-disciplines of Chronobiology and thus enhance the coherence of the research field as a whole. (3) To intensify interactions between young and established researchers, and thus sustain high-quality chronobiological research. (4) To promote both national and international collaboration by bringing together scientists from many different research groups and countries. (5) To promote translational research by bringing together investigators employing model organisms with those studying human subjects in circadian research. The conference will achieve these goals by assembling approximately 150 scientists encompassing individuals from different countries, age groups, genders, and using different research models. We will encourage active participation of minority groups by inviting individuals and contacting minority colleges directly (e.g., Morehouse). The program will focus on new and emerging developments in key research areas (see Tentative Program). In accordance with the highly successful Gordon Conference format, lectures will be presented in 9 morning and evening sessions with ample time for discussion. Three late-afternoon poster sessions will allow participants to present additional data. Special attention has been given to achieving gender balance and to including experts from very diverse disciplines to achieve a broadly-based understanding of the frontier of our science and insights as to future opportunities. Outcomes will have health relevance for ameliorating dysfunctions that manifest as sleep, affective, cognitive, neurological, metabolic, endocrine and oncological disorders.