ECM in Structure & Function of the Craniofacial Complex

描述（由申请人提供）：申请人寻求将于2005年3月9日至11日在巴尔的摩马里兰州国际牙科研究协会举行的特别研讨会的资金。研讨会的目的是汇集最先进的演讲，解决颅面复合体中细胞外基质的作用。ECM是一个复杂的结构，包含无数的结构蛋白，其功能现在开始被解开。使用大量的实验方法，从经典的蛋白质化学，纳米技术，分子和细胞生物学到动物模型的创建，个别ECM蛋白质的新的和意想不到的作用正在出现。通过聚集这一领域的关键科学家，一幅关于ECM在头部和面部的形式和功能中的作用的过去、现在和未来的协调画面将出现。 该方案将侧重于以下领域： 细胞外基质的作用： A）缝线形成 B）骨 C）牙齿：釉质 D.牙本质和牙骨质 E）颞下颌关节。

DESCRIPTION (provided by applicant): The applicants seek funding for a special symposium that would be held at the International Association of Dental Research, Baltimore Maryland, March 9-11, 2005. The goal of the symposium is to bring together state of the art presentations addressing the role of the Extracellular Matrix in the craniofacial complex. The ECM is a complex structure harboring a myriad of structural proteins whose functions are now beginning to be unraveled. Using a host of experimental approaches ranging from classic protein chemistry, nanotechnology, molecular and cell biology to the creation of animal models new and unexpected roles for individual ECM proteins is emerging. By assembling key scientists in this area a coordinated picture will emerge about the past, present and future of role of ECM in the form and function of the head and face. The program will focus on the following areas: The Role of the Extracellular Matrix in: A) Suture formation B) Bone C) Teeth: Enamel D) Dentin and Cementum E) Temporomandibular Joint.