Metals in Biology & Graduate Res Seminar Gordon Confer

申请者描述(由申请者提供)：申请资助将于2005年1月、2006年1月和2007年1月在加利福尼亚州文图拉喜来登四点港城酒店举行的生物金属戈登研究会议(MIB-GRC)和研究生研究研讨会(GRS)的与会者的会议费和/或旅费。MIB-GRC通常被认为是涵盖矿物生物化学和生物无机化学领域的首次小型会议。自1962年以来，这些会议一直是介绍和讨论前沿研究的定期论坛，涵盖金属离子在生物化学、分子生物学、细胞生物学和医学中作用的方方面面。这次会议的受欢迎程度导致从1987年1月开始从两年一次的日历改为年度日历。然而，这次会议的订阅量仍然很大，严重限制了出席会议的研究生和博士后研究人员的数量。于是，1996年，生物无机化学专业金属生物研究生研究会正式成立。本次会议面向该领域的研究生和博士后，他们齐聚一堂，在为期三天的会议上发表演讲和科学海报演示。周四下午和晚上的两个会议重叠在一起，包括联合海报会议，GRS与会者的演讲，晚宴，以及MIB-GRC的一位主旨讲师(2005年邀请Joann Stubbe)。2005年MIB-GRC会议的重点议题包括：(1)合成类似物；(2)非血红素铁；(3)金属酶中的新中间体；(4)细胞色素c氧化酶；(5)新的光谱方法；(6)铜酶；(7)金属、DNA和医药。2005年GRS的课程将包括：(1)金属蛋白质(结构和功能)；(2)金属吸收和调节；(3)仿生无机化学；(4)环境/医学生物无机化学；(5)生物无机化学中的物理方法。通过促进该领域发生的许多跨学科互动，会议在鼓励生物医学研究领域的新企业方面发挥了关键作用。为了确保强有力的方案，重要的是，参加会议的费用不能妨碍受邀的发言者和讨论主席出席。

DESCRIPTION (provided by applicant): Funds are requested to support conference fees and/or travel costs of participants to the Metals in Biology Gordon Research Conferences (MIB-GRC) and Graduate Research Seminars (GRS) to be held in January 2005, 2006 and 2007, at the Sheraton Four Points Harbortown Hotel, Ventura, CA. The MIB-GRC is generally considered to be the premiere small meeting covering the fields of metallobiochemistry and bioinorganic chemistry. Since 1962, these meetings have been a regular forum for the presentation and discussion of forefront research covering all aspects of the roles of metal ions in biochemistry, molecular biology, cell biology and medicine. The popularity of this meeting led to a change from biennial to an annual calendar starting in January 1987. However, the conference remains greatly oversubscribed, severely curtailing the number of graduate students and postdoctoral researchers in attendance. As a result, in 1996, the Metals in Biology Graduate Research Seminar in Bioinorganic Chemistry was established. This conference is devoted to graduate students and postdoctorals in the field, who come together to present lectures and scientific poster presentations in a three-day meeting. The two meetings overlap for Thursday afternoon and evening including a joint poster session with presentations from the GRS attendees, dinner, and a keynote lecturer from the MIB-GRC (for 2005 Joann Stubbe is being invited). The topics to be emphasized for the 2005 MIB-GRC conference include: (1) Synthetic Analogues; (2) Non-Heme Iron; (3) Novel Intermediates in Metalloenzymes; (4) Cytochrome c Oxidase; (5) New Spectroscopic Methods; (6) Copper Enzymes; and (7) Metals, DNA and Medicine. The program for the 2005 GRS will include sessions on: (1) Metalloproteins (Structure and Function); (2) Metal Uptake and Regulation; (3) Biomimetic Inorganic Chemistry; (4) Environmental/Medical Bioinorganic Chemistry; and (5) Physical Methods in Bioinorganic Chemistry. By facilitating the many interdisciplinary interactions that occur in this field, the conference plays a key role in encouraging new enterprises in biomedical research. To ensure strong programs, it is important that the cost of participating in the conference not be an impediment to the attendance of the invited speakers and discussion chairs.