The biology and biotechnological potential of marine fungi bioprocessing. (Ref: 4284)

真菌通常是公认的生物处理器，具有降解和同化各种生物质基质的能力，随后产生各种有价值的生物资源，海洋真菌是一种新的、目前尚未充分研究的生物处理资源，无论是在其基础生物学方面还是在生物技术应用方面。这个博士项目将探索和研究海洋真菌的生物加工潜力，这些真菌来自普利茅斯海洋生物协会（MBA）最近建立的海洋真菌培养物。超过400种酵母和菌丝菌株可从一系列温带和极地海洋环境中获得，包括深海和海冰。总之，博士项目将使用高通量方法筛选海洋真菌培养物，确定感兴趣的特定真菌菌株和底物组合。菌株/底物组合将在基础生物学机制（例如底物附着和酶生产）和潜在生物技术应用（例如生物分子生产）方面进行研究。

Fungi are generally well-established bioprocessors with the ability to degrade and assimilate a broad range of biomass substrates and subsequently produce a wide variety of valuable biological resources.Marine fungi represent a novel and currently understudied resource for bioprocessing, both in terms of their fundamental underpinning biology and biotechnological applications. This PhD project will explore and study the bioprocessing potential of marine fungi from the recently established marine fungi culture collection at the Marine Biological Association (MBA) in Plymouth. Over 400 yeast and hyphal strains are available from a range of temperate and polar marine environments, including the deep open ocean and sea ice. In summary, the PhD project will screen the marine fungi culture collection, using a high-throughput approach, identifying specific fungal strain and substrate combinations of interest. The strain/substrates combinations will be studied in terms of underpinning biological mechanisms (e.g. substrate attachment and enzyme production) and potential biotechnological application (e.g. biomolecule production).