Nanocoatings for Biomedical Implants

描述(申请人提供)：有人提议在钛种植体上开发一种纳米羟基磷灰石涂层(HAP)。在牙种植体手术中，骨整合是至关重要的，因为它受到建筑材料、设计和手术技术的适当选择的影响。种植体的快速固定和耐用性一直是种植体制造商和种植体外科专家追求的目标。所提出的纳米颗粒涂层有望提供良好的附着力、耐久性的可控相以及可控的孔尺寸以促进组织生长。涂层将使用静电喷涂和微波烧结或激光烧结的混合工艺来制造。将测量涂层的平均孔径、表面粗糙度、物相和附着力。将测试涂层牙种植体的力学性能，包括强度和断裂韧性。所提出的纳米颗粒涂层技术具有沉积速度快、适用于各种复合涂层、与简单和复杂的几何形状兼容、灵活性和低成本等优点。我们预计，这种包覆技术的应用将消除无定形HAP的形成，这种无定形HAP很容易溶于体液，影响界面粘附性。

DESCRIPTION (provided by applicant): It is proposed to develop a nanoparticle coating of hydroxyapatite (HAp) on titanium dental implants. Osseointegration is of critical importance in dental implant surgical operation because it is affected by the proper selection of construction materials, design, and surgical techniques. Fast fixation and durability of dental implants have long been sought by dental implant manufacturers and implant surgical specialists. The proposed nanoparticle coating is expected to provide good adhesion, controlled phases for durability, and controlled pore size for promoting tissue growth. The coating will be fabricated using a hybrid process of electrostatic spray coating and microwave sintering or laser sintering. The average pore size, surface roughness, phase, and the adhesion of the coating will be measured. The mechanical properties, including the strength and the fracture toughness of the coated dental implants, will be tested. The proposed nanoparticle coating technique offers high deposition rate, suitability for various composite coatings, compatibility to simple and complex geometry, flexibility, and low cost. We anticipate that the application of this coating technique will eliminate the formation of amorphous HAp, which is easily dissolved into body fluid and affects the interfacial adhesion.