Regulation of Cellular Growth and Differentiation

描述(由申请人提供)：本申请是一项名为“细胞生长和分化调控”的培训补助金的竞争性续期，最初于1993年获得资助。这项拨款提案的目标不变，即为当代癌症生物学的博士后和博士后学员提供扎实的培训，使他们能够在该学科追求独立的职业生涯。一个由19名明确关注癌症研究的研究人员组成的小组正在寻求资金，通过这个项目培训4名博士后和4名博士后研究员。这些教官来自全国七个部门。这些系包括细胞生物学系、环境卫生系、发育生物学系、内科系、分子遗传学系、基因组科学系和分子和细胞生理学系。所有的培训教员都得到了NIH和其他资助机构的良好资助，如美国癌症协会和国防部乳腺癌项目。大多数培训教师的研究支持来自国家癌症研究所。正如本提案正文所详述的那样，培训补助金教员之间存在着积极的合作。在医疗中心管理局的大力支持下，癌症项目在过去五年中有了显著的增长，中心招募了新的人员。这使培训补助金受益，并改善了我们招聘更高素质学员的努力。将继续努力招聘最优秀的受训人员，包括少数族裔候选人。博士前应聘者拥有生物、化学或物理专业的学士学位。博士后候选人必须拥有博士、医学博士或医学博士学位，并证明学术成就卓越。为博士后和博士后学员制定了明确的培训计划和新的培训方法，其中包括强制参加癌症生物学课程、癌症杂志俱乐部、癌症研讨会系列、“癌症患者护理意识”、科学写作和年度务虚会。咨询委员会和执行委员会将定期审查对方案的评价和受训人员的进展情况。过去参加该项目的学员都在优秀的机构从事癌症研究工作。我们致力于培养训练有素的研究人员，他们符合NCI设想的癌症研究培训标准。

DESCRIPTION (provided by applicant): This application is a competitive renewal for a training grant entitled "Regulation of cellular growth and differentiation", originally funded in 1993. The goal of this grant proposal remains unchanged, that is to provide solid training to pre- and postdoctoral trainees in contemporary cancer biology, so that they can pursue independent careers in this discipline. A group of 19 investigators with clear focus in cancer research are seeking funds to train 4 predoctoral and 4 postdoctoral fellows through this program. The preceptors are derived from seven departments of the. These include the Department of Cell Biology, Department of Environmental Health, Department of Developmental Biology, Department of Internal Medicine, Department of Molecular Genetics, Department of Genome Sciences, and Department of Molecular and Cellular Physiology. All of the training faculty members are well funded by NIH and other funding agencies, such as American Cancer Society and DOD Breast Cancer Program. Research supports of a majority of the training faculty come from National Cancer Institute. As detailed in the body of this proposal, active collaborations exist among the training grant faculty. With the strong backing of the Medical Center Administration, the cancer program has seen a remarkable growth in the past five years with new recruitments at the center. This has benefited the training grant and has improved our efforts to recruit trainees of higher caliber. Efforts to recruit the best trainees, including minority candidates will continue. Entering predoctoral candidates have undergraduate bachelor's degree in biological, chemical or physical sciences. Postdoctoral candidates must have a Ph.D., M.D., or D.V.M. and proven academic excellence. A well-defined training program, with new training approaches, is outlined for pre- and postdoctoral trainees that include mandatory participation in a course on Biology of Cancer, Cancer Journal Club, Cancer Seminar Series, "Awareness to Cancer Patient Care", Scientific Writing and Annual Retreat. The evaluation of the program and the progress of the trainees will be periodically reviewed by the Advisory and the Executive Committees. Past trainees of this program have gone on to careers in cancer research at excellent institutions. We are committed to produce well-trained researchers, who conform to the criteria for cancer research training envisioned by the NCI.