Cellular and Molecular Parasitology Training Program NIA

描述（由申请人提供）：拟开设细胞与分子寄生虫学（CMP）博士前培训课程，通过其教学和研究组成部分，为学员提供获得现代寄生虫学专业知识的绝佳机会。根据培训学员的背景经验，该项目提供三个层次的课程，包括(1)基础课程介绍寄生虫学的概念，并以对人类和动物健康重要的寄生虫为例，(2)分子寄生虫学，免疫寄生虫学，医学昆虫学和其他专业学科的高级课程。(3)每周的期刊俱乐部和研究“焦点”小组，对主要文献和实习生的研究成果进行批判性分析。所有实习生将被要求参加“科学中的良好实践：研究伦理和生存技能”课程，作为有关研究伦理行为问题的正式介绍。每月还将举办由校内和校外寄生虫学和热带医学专家参加的研讨会。培训计划的研究部分包括在13个培训实验室中的任何一个研究寄生虫-宿主关联的细胞，生化，免疫学或分子方面的机会。可供研究的寄生虫模型范围广泛，包括对热带地区健康具有重要意义的模型：疟疾、锥虫病、血吸虫病和丝虫病。参与的教师拥有出色的培训记录和资金充足的项目，涵盖各种研究领域，如媒介生物学，寄生虫感染和疾病的免疫学，代谢的生物化学和基因调控，细胞周期和分泌途径，微生物-昆虫相互作用，寄生虫神经生物学。要求支持五年，每年支持六(6)名博士预科学员。特别合格的学员将由CMP培训委员会从全国申请者中选出。选择将基于学术卓越，推荐，先前的研究经验/出版物以及他们对研究事业的承诺。CMP培训支持学生的持续时间为2至3年。计划描述了鼓励申请和支持在科学领域代表性不足的少数民族学生。优秀的培训设施将通过个人研究实验室、部门共享资源和校园范围内的设施提供，包括Biotron、生物技术中心、基因组研究中心、综合显微镜资源和几个aaalac批准的动物护理设施。

DESCRIPTION (provided by applicant): Proposed is a predoctoral training program in cellular and molecular parasitology (CMP) that will provide trainees excellent opportunities to gain expertise in modern parasitology through its instructional and research components. Depending on the background experience of metriculating trainees, the program offers a three-tiered curriculum which includes ( 1) a basic course introducing concepts of parasitology drawing examples from parasites important to human and animal health, (2) advanced courses in molecular parasitology, immunoparasitology, medical entomology, and other specialized disciplines, and (3) weekly journal clubs and research "focus" groups featuring critical analyses of the primary literature and trainee research findings, All trainees will be required to take the course "Good Practices in Science: Research Ethics and Survival Skills" as a formal introduction to issues surrounding the ethical conduct of research. Monthly seminars featuring both on- and off-campus experts in parasitology and tropical medicine also will be offered. The research component of the training program consists of opportunities to investigate cellular, biochemical, immunological, or molecular aspects of parasite-host associations in any of 13 trainer laboratories. A wide range of parasite models are available for study including those of major importance to health in the tropics: malaria, trypanosomiasis, schistosomiasis, and filariasis. Participating faculty have outstanding training records and well-funded programs covering a variety of research areas such as vector biology, immunology of parasitic infection and disease, biochemistry and gene regulation of metabolic, cell cycle and secretory pathways, microbe-insect interactions, and parasite neurobiology. Support is requested for five years to support six (6 ) predoctoral trainees per year. Exceptionally qualified trainees will be selected for awards from a national pool of applicants by the CMP training committee-of-the-whole. Selection will be based on scholastic excellence, recommendations, prior research experience/publications and their commitment to careers in research. The duration of CMP training support for students will be from 2 to 3 years. Plans are described to encourage applications from and support of minority students underrepresented in the sciences. Outstanding training facilities will be provided through individual investigator labs, departmental shared resources and campus-wide facilities including the Biotron, Biotechnology Center, Center for Genomic Studies, Integrated Microscopy Resource, and several AAALAC-approved animal care facilities.