Strengthening Bioethics Capacity and Justice in Health

描述(由申请人提供)：在稀缺和不平等的环境中进行人类研究需要结合基本的跨文化价值观和促进社会变革的背景敏感的伦理。我们建议通过扩大与北卡罗来纳大学(UNC)和比利时卢万天主教大学(UCL)的伙伴关系，建设刚果民主共和国金沙萨公共卫生学院(KSPH)的生物伦理培训和研究能力。四名刚果学者将在伦敦大学学院完成为期一年的生物伦理学硕士研究生强化培训课程，并在北卡罗来纳大学完成为期5个月的有指导的生物伦理学研究开发、课程建设和IRB培训。回到刚果民主共和国后，新的KSPH生物伦理中心(CB)的学者将加强当地IRB的能力；开展创新的和与社会相关的独立生物伦理研究；开发一个为期两周的生物伦理模块，整合到KSPH的公共卫生计划中；建立生物伦理文献和咨询服务；创建专注于发展中的世界生物伦理问题的原创教学材料；设计一个生物伦理网站并发展电子学习能力；在第四年，为来自整个讲法语的非洲的学者提供为期两周的生物伦理强化课程。新的KSPH生物伦理中心的各种活动将服务于其在刚果民主共和国和非洲法语国家促进负责任的生物医学研究和临床实践的使命。该委员会将鼓励思考贫困和不公正情况下自主的意义；社区、研究机构和脆弱对象之间的共同责任；对生物医学研究引起的伦理冲突的创造性、文化共鸣的解决方案；承认程序性知情同意的重要性和局限性，以及体现研究人员和研究对象之间相互尊重的“协商同意”的必要性。公民权利委员会对于负责任地处理根植于地方和全球不公正的公共卫生问题至关重要，并可促进社会变革和建立新的人权文化。

DESCRIPTION (provided by applicant): Human subjects research in environments of scarcity and inequality requires context-sensitive ethics that incorporates basic transcultural values and promotes social change. We propose to build bioethical training and research capacity at the Kinshasa School of Public Health (KSPH), Democratic Republic of Congo (DRC) through expansion of its partnerships with the University of North Carolina (UNC), and the Catholic University of Louvain, Belgium (UCL). Four Congolese scholars will complete a one-year intensive postgraduate, master-level training program in Bioethics at UCL, and 5 months of mentored bioethics research development, curriculum building, and IRB training at UNC. Upon return to DRC, scholars at the new KSPH Center of Bioethics (CB), will reinforce local IRB capacity; perform innovative and socially relevant independent bioethics research; develop a two-week bioethics module integrated into the MPH program at KSPH; establish a bioethics documentation and consultation service; create original pedagogical material focusing on developing world bioethical issues; design a bioethics website and develop e-learning capacities, and in the fourth year, offer a 2-week intensive course in bioethics for scholars from throughout Francophone Africa. The diverse activities at the new KSPH Center of Bioethics will serve its mission to promote responsible biomedical research and clinical practice in DRC and in francophone Africa. The CB will encourage reflection on the meaning of autonomy in circumstances of poverty and injustice; co-responsibility between communities, research institutions and vulnerable subjects; creative, culturally resonant solutions to ethical conflicts raised by biomedical research; recognition of the importance and limits of procedural informed consent, and the need for 'negotiated consent' embodying mutual respect between researcher and subject. The CB is critical to deal responsibly with public health problems rooted in local and global injustice, and can contribute to social change and the establishment of a new human rights culture.