PR COMPREHENSIVE CTR FOR HIV DISPARITIES: PSM: LAB CORE

描述(由申请人提供)： 这项提议将为艾滋病毒/艾滋病领域的健康差距综合研究中心建立业务和研究基础设施。这是独特而重要的，因为PR中的三所经认证的医学院(UPR医学院、UCC医学院和庞塞医学院)将第一次作为合作伙伴在共同的追求中合作。该中心的一些具体目标是：(1)通过这三所学校之间的合作加强临床和转化性研究，(2)为未来建立这一传统或“合作文化”，(3)制定针对波多黎各人口的可持续、可复制和文化上适当的预防和/或干预研究方案，以减轻疾病负担，(4)开发和验证一系列文化上适当的工具，以衡量不同的变量，例如但不限于：社会人口、艾滋病毒危险行为、共病、坚持、污名、暴力和虐待史；并将其提供给感兴趣的研究人员和医疗保健提供者，(6)利用来自本地和国外(公关和美国机构)的资源，为初级调查人员建立导师计划，并创造激励的学术环境，鼓励学生和研究员从事健康差距研究，特别是艾滋病毒/艾滋病研究，以及(7)增加岛屿机构与在美国大陆拥有更成熟研究项目的机构之间进行多学科研究合作的机会。在第一阶段期间，将建立该中心的业务基础设施，并支持每个机构一个试点项目。在第二阶段，这些试点项目将成为研究项目，新的年轻调查人员将通过试点项目加入中心。一个强大的教师发展核心组成部分将确保该中心研究人员的增长和生产力。其他核心活动将是数据 中心、一个实验室、一个儿童权利中心、一个在一名作家/编辑协助下的出版办公室，以及3名健康差距调查员的招聘。

DESCRIPTION (provided by applicant): This proposal will establish the operational and research infrastructure for a Comprehensive Center for the study of Health Disparities in the area of HIVIAIDS. It is unique and important because for the first time the three accredited Medical Schools in PR (UPR School of Medicine, UCC School of Medicine, and Ponce School of Medicine) will collaborate as partners in a common pursuit. Some of the specific aims of the center are: (1) the enhancing of clinical and translational research through collaboration among these three schools, (2) to establish this tradition or "culture of collaboration" for the future, (3) to develop sustainable, replicable and culturally appropriate prevention and/or intervention research programs targeted to the Puerto Rican population to decrease the burden of disease, (4) to develop and validate a series of culturally appropriate instruments to measure diverse variables such as but not limited to: sociodemographic, HIV risk behaviors, co-morbidities, adherence, stigma, history of violence and abuse; and to make them available to interested investigators and health care providers, (6) to establish a Mentorship program for junior investigators with resources from both local and abroad (PR and US institutions) and to create the stimulating academic environment that will encourage students and fellows to pursue a career in health disparities research and in particular, HIV/AIDS research and (7) to enhance the opportunities for multidisciplinary research collaborations between the island institutions and those with a more established research programs in the US mainland. During a Phase I the operational infrastructure of the center will be established and one pilot project per institution will be supported. During the Phase II, these pilot projects will become research projects and new young investigators will join the Center through pilot projects. A strong Core component of faculty development will assure the growth and productivity of the center's investigators. Other Core activities will be a Data Center, a Lab, a CRC, a publications office with the assistance of a writer/editor, and the recruitment of 3 health disparities investigators.