Neurodegenerative diseases and neural repair

描述（由申请人提供）： 神经退行性疾病对国家的健康和经济产生重大影响。认识到这一事实，格鲁吉亚医学院有一个长期目标，即招募和培养校园内神经科学家核心的成长，以促进我们对这些至关重要的疾病的生物和分子基础的理解。通过战略规划和强大的机构支持，教师的核心现在在校园里，这是配备了广泛的技术和模型，可以集中在这些复杂的疾病的研究。一位著名的科学家，罗伯特·于，领导着这支神经科学家队伍。我们现在已经达到了一个增长点，NIH赞助的培训补助金的实施不仅有利于实现我们的研究目标，而且在全球范围内，通过培训未来的神经科学家来继续推进科学。在此，我们请求为3名博士后和1名博士前实习生提供支助，重点是招聘少数民族候选人。每位学员将由一位在培训方面拥有丰富经验并得到国家认可的计划教师指导。培训将通过每周实验室会议和由共同研究者组成的指导委员会进行监测和指导。杰出的神经科学家对计划目标、成就和进展的外部审查也将每年进行一次。由于该领域需要临床和基础神经科学家，因此培训计划的目标是培养精通与神经退行性疾病及其修复研究相关的多个领域的博士和医学博士/博士。凭借强大的机构支持，优秀的核心资源和经验丰富的教师队伍，这些关键因素都是强大的培训计划的关键因素。因此，NIH的支持将有助于加强神经科学项目，该项目在推进神经退行性研究领域和培养其未来领导者方面具有独特的地位。

DESCRIPTION (provided by applicant): Neurodegenerative disorders have a significant health and economic impact upon the nation. In recognition of this fact, the Medical College of Georgia has had a long-term goal of recruiting and fostering the growth of a core of neuroscientists on campus so as to advance our understanding of the biological and molecular basis of these critically important disorders. Through strategic planning and strong institutional support, a nucleus of faculty are now in place on campus, which are equipped with a wide array of techniques and models that can be focused on the study of these complex disorders. An eminent scientist, Robert Yu, leads this cadre of neuroscientists. We have now reached the point of growth where the implementation of a NIH-sponsored training grant would be beneficial, not only to the achievement of our research goals, but also on a global scale, to the continued advancement of science through the training of future neuroscientists. Here, we request support for 3 post- and 1 predoctoral trainees, with an emphasis on the recruitment of minority candidates. Each trainee will be mentored by one of the Program faculty, who have extensive experience in training and are nationally recognized. Training will be monitored and guided by weekly lab meetings, and by a Steering Committee composed of the co-investigators. Outside review of the program goals, achievements and progress by eminent neuroscientists will also occur annually. Since clinical and basic neuroscientists are needed in the field, it is the goal of the training program to produce PhDs and MD/PhDs who are well versed in multiple areas related to the study of neurodegenerative diseases and their repair. With strong institutional support, excellent core resources, and an experienced faculty, the key elements are all in place for a strong training program. Support by the NIH would thus help strengthen a neuroscience program that is uniquely positioned to both advance the field of neurodegenerative research and train its future leaders.