BIOMOLECULE CHARACTERIZATION AND SEPARATION CORE FACILITY

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。德克萨斯大学埃尔帕索分校提议继续支持专门从事生物分子分离和表征的多用户研究设施，即分子生物学核心设施。该设施维护设备，如离心机，超离心机，伽马和闪烁计数器，HPLC与众多检测器，毛细管电泳，紫外/可见分光光度计，微孔板读取器和许多其他项目的共享设备。还有许多其他资源可用于记录和分析使用这些仪器收集的实验数据。目前，该核心还具备核酸的合成和扩增功能。这些能力可能经过重新安排和与受影响的用户群体进行讨论，以便更好地满足用户的需要。该设施的目的是为尽可能广泛的用户群体提供使用维护良好、最先进设备的机会。放置这些仪器的两个房间每个月都有超过100名个人用户进入1000次，代表超过15个研究小组。该设施将配备一名全职协调员，负责日常维护，安排工厂代表的预防性维护，用户指导和协助以及帐户和库存维护。将向核心主任提供部分薪金，以便持续监督这些活动

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Texas at El Paso proposes continuing support for a multi-user research facility specializing in the separation and characterization of biomolecules, the molecular biology core facility. This facility maintains equipment such as centrifuges, ultracentrifuges, gamma and scintillation counters, HPLC with numerous detectors, capillary electrophoresis, UV/vis spectrophotometers, microplate readers and many other items of shared equipment. Numerous other resources are available as well to document and analyze experimental data collected using these instruments. Currently, this core is also equipped for the synthesis and amplification of nucleic acids. These capabilities may be reorganized to better serve the needs of users as a result of possible relocation and discussions with affected user groups. The purpose of this facility is to provide the broadest possible group of users with access to well maintained, state of the art, equipment. Each of two rooms housing these instruments is entered more than 1000 times per month by more than 100 individual users, representing more than 15 research groups. This facility will be staffed by a full-time coordinator who will be responsible for routine maintenance, scheduling preventative maintenance by factory representatives, user orientation and assistance as well as account and inventory maintenance. Partial salary will be provided to the core director for ongoing oversight of these activities