UConn Craniofacial Tissue Repair Regeneration Program

描述（由申请人提供）：我们的目标是加强口腔医学的UCONN学校的研究基础设施，并成为颅面组织修复和再生（CTRR）研究的领导者。在过去两年中进行的紧急需求评估规划进程导致选定了紧急需求审查和报告的主题。最大的需求是增加研究教师谁将弥合现有的专业知识和创造协同作用，以扩大和提高我们的研究生产力的学科差距。基础设施增强计划将：a）在CTRR中建立一个项目，导致再生医学和骨骼发展部门; B）在牙科医学院招募一名高级磁铁研究员，他将领导开发新部门的努力，并与肌肉骨骼签名计划协调计划目标; c）在CTRR中招募2-3名额外的教师到牙科医学院; d）与肌肉骨骼签名计划的主任合作，招募医学院的研究人员，他们的研究与CTRR的目标和目的相结合; e）招募2-3名具有流行病学和生物统计学专业知识的教师，他们将支持临床试验的发展; f）招募成熟的临床研究者与CTRR研究者合作，将科学发现转化为临床应用; g）为现有的临床教师提供指导研究经验，以提高研究技能，成为转化研究的积极合作者。该计划的实施将开始与磁铁调查员的招聘，然后再招聘2名教师到牙科医学院的补充科学领域，如颅面生物学或转化研究。将创建一个CTRR核心实验室，以支持协作活动和共享设备。康州大学21世纪世纪计划是一项为期10年的2.97亿美元的基础设施改善计划，将支持新的研究大楼和现有实验室的翻新，以创造最先进的研究空间。来自牙科医学院院长，卫生事务副总裁和康涅狄格大学校长的支持信通过教师职位，空间和设备的承诺表现出强有力的支持。我们的愿景是创造一个丰富的跨学科研究环境，涵盖基础，转化和社区研究。

DESCRIPTION (provided by applicant): Our objective is to enhance the research infrastructure at the UCONN School of Dental Medicine and to become a leader in research in Craniofacial Tissue Repair and Regeneration (CTRR). The Critical Needs Assessment planning process carried out for the past two years led to the selection of the theme of CTRR. The greatest need was for additional research faculty members who would bridge the disciplinary gaps in existing expertise and create synergy to expand and enhance our research productivity. The Infrastructure Enhancement Plan will: a) establish a program in CTRR leading to a department of Regenerative Medicine and Skeletal Development; b) recruit one senior magnet investigator in the School Of Dental Medicine who will lead the effort to develop the new department and coordinate program goals with the Musculoskeletal Signature Program; c) recruit 2-3 additional faculty members to the School of Dental Medicine in CTRR; d) work with the Director of the Musculoskeletal Signature Program to recruit investigators in the School of Medicine whose research is integrated with the goals and objectives of the CTRR; e) recruit 2-3 faculty members with expertise in epidemiology and biostatistics who will support the development of clinical trials; f) enlist established clinical investigators to collaborate with CTRR investigators in the translation of scientific discoveries into clinical applications; g) provide mentored research experiences for existing clinical faculty to enhance research skills to become active collaborators in translational research. Implementation of the Plan will begin with the recruitment of a magnet investigator followed by recruitment of 2 additional faculty members to the School of Dental Medicine in complementary scientific areas, such as craniofacial biology or translational research. A CTRR core lab will be created to support collaborative activities and house shared equipment. The UCONN 21st Century initiative, an infrastructure enhancement program of $297 million dollars over 10 years, will support a new research building and renovation of existing labs to create state of the art research space. Letters of Support from the dean of the School of Dental Medicine, the Vice- President for Health Affairs and the President of the University of Connecticut demonstrate strong support through commitment of faculty positions, space, and equipment. Our vision is to create a rich environment of interdisciplinary research that spans basic, translational and community based research.