New Iizarov technique for pediatric critical care

描述（由申请人提供）：拟议研究旨在开发和评价一种新的外固定器，该外固定器可以更容易和有效地应用于儿科重症监护和康复的早期阶段。在I期研究期间，将测试并进一步开发新开发的外部双针Iizarov固定器（Pitkin和Gritsanov，2005）。测试将包括“易于应用”和固定稳定性测试，与美国军事医学（霍夫曼II）采用的外固定器相比。在新器械中，成对的针簇取代了穿透骨的金属丝或针。固定器将通过手动致动器应用于骨骨膜，而无需钻孔和打开髓管。这种新型固定器将潜在地结合联合收割机现有的半针外固定器（不需要钻孔）和无针AO外固定器（Alonso和Regazzoni，1990; Cheung，Wong和Choi，2001）（不穿透髓管）的优点。研究者假设，使用新开发的双针固定器，固定的稳定性和操作的简单性将超过美国军事医学采用的外半针固定器（Hofmann II）的实用性水平。将在关于应用方便性和固定稳定性的比较研究中对该假设进行评价。如果达到了I期研究的目的，将进行进一步的研究（II期），以验证早期应用外固定架的有效性。

DESCRIPTION (provided by applicant): The proposed study is aimed at developing and evaluating a new external fixator, that could be more easily and effectively applied at the early stages of evacuation to specialized facilities, for pediatric critical care and rehabilitation. During the Phase I study, a newly developed external double-needle Iizarov fixator (Pitkin and Gritsanov, 2005) will be tested and further developed. Testing will include "ease-to-apply" and stability of fixation tests, as compared to the external fixator adopted by US Military medicine (Hoffmann II). In the new device, clusters of paired needles replace wires or pins penetrating the bone The fixator is to be applied to the bone periosteum by manual actuators, without drilling the bone and opening of the medullary canal. The new fixator will potentially combine the advantages of the existing half-pin external fixators, which don't require drilling, and the pinless AO external fixator (Alonso and Regazzoni, 1990; Cheung, Wong and Choi, 2001), which doesn't penetrate the medullar canal. The Investigators hypothesize that with the newly developed double-needle fixator, the stability of fixation and simplicity of operating the apparatus will surpass the level of practicality of the external half-pin fixator (Hofmann II) adopted by the US Military Medicine. The hypothesis will be evaluated during the comparative studies on the ease of application and the stability of fixation. If this aim of the Phase I study is achieved, the further study (Phase II) will be conducted to verify the effectiveness of the early application of external fixation.