Perturbation to force sharing patterns in 5-digit grasps

描述(由申请人提供)：患有某些神经和肌肉骨骼疾病的人，小灵通握力协调能力严重受损。对力量协调能力发展的基本了解对于这些人的手功能的康复和恢复是至关重要的。本提议的目的是更好地了解握持过程中多个握力的空间和时间协调的机制。这一目标将通过检查在五位数抓取过程中对稳定的力分享模式的扰动的非自愿纠正力反应来实现。将引入一种新的程序，在单个手指上引起瞬间的力变化，扰乱力共享模式。该建议的具体目的是确定1)力摄动参数(数字摄动、力的方向)和2)初始力共享模式对为补偿摄动而产生的非自愿纠正力响应的影响。我们的初步数据表明，这涉及到非自愿的纠正性反应。我们将测试纠正力反应将取决于受扰手指在保持抓握稳定性中的功能作用。

DESCRIPTION (provided by applicant): PHS Force coordination in grasping is severely impaired in individuals with certain neurological and musculoskeletal diseases. Basic understanding of the development of force coordination is essential for the rehabilitation and restoration of hand function in these individuals. The objective of the present proposal is to better understand the mechanisms underlying the spatial and temporal coordination of multiple grip forces during grasping. This objective will be pursued by examining involuntary corrective force responses to perturbations to stable force sharing patterns during five-digit grasps. A novel procedure will be introduced that elicits transient force changes in individual digits, disrupting the force sharing pattern. The specific aims of the proposal are to determine the effects of varying 1) force perturbation parameters (digit perturbed, direction of force) and 2) initial force sharing pattern on the involuntary corrective force responses developed to compensate for the perturbation. Our preliminary data suggests that involuntary corrective responses are involved. We will test that the corrective force responses will be dependent upon the function role of the perturbed digit in maintaining grasp stability.