Socioeconomic Position and Late-Life Depression: Is C-Reactive Protein A Mediator?
Socioeconomic Position and Late-Life Depression: Is C-Reactive Protein A Mediator?
批准号:
2758265
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2022
资助国家:
英国
项目状态:
未结题
起止时间:
2022 至 --
中文摘要
社会经济地位(SEP)和晚年抑郁症(LLD)之间的关系有多强?C反应蛋白、体感诱发电位与低密度脂蛋白有关系吗?在对身体疾病/疾病的多个指数进行广泛控制后,这种关系是否仍然存在?在控制了童年社会经济地位(CSEP)的影响后,这一点仍然显著吗?C反应蛋白、心血管危险因素和脑白质高信号是否在SEP和LLD之间起中介作用?
英文摘要
What is the strength of the relationship between socio economic position (SEP) and late life depression (LLD)? Is there a relationship between CRP, SEP and LLD? Does this relationship remain after extensive controlling for multiple indices of physical illness/disease? Does this remain significant after controlling for the effects of childhood socioeconomic position (cSEP)? Do CRP, cardiovascular risk factors, and white matter hyperintensities mediate between SEP and LLD?
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