User Interfaces, Visualisation and Modelling for Targeting Cancer Treatments
User Interfaces, Visualisation and Modelling for Targeting Cancer Treatments
批准号:
2759005
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2022
资助国家:
英国
项目状态:
未结题
起止时间:
2022 至 --
中文摘要
这一领域所有研究的目的都是创造个性化的、有针对性的癌症治疗方法。药物需要以正确的剂量准确地输送,以减少全身的癌症。这项研究具有现实应用价值,可以帮助实现这一目标。该项目将对药物动力学(PK)(药物在体内的移动)和药效学(PD)(生物反应)进行建模和可视化,这通常被称为(PK-PD动力学)。PK-PD关系可以用各种数学模型来描述,这些模型可以用来根据药物的PK曲线来预测药物的药理反应。该项目的重点将是生产软件工具,通过考虑科学家(药物开发商)如何使用现有的和新的PK-PD模型并与其相互作用来加速这一领域的科学研究。
英文摘要
The aim of all research in this area is to create personalised, targeted cures for cancer. Drugs need to be delivered precisely and with the correct dosage to reduce cancer throughout the body. This research has real world application to help this aim. The project will model and visualise pharmacokinetics (PK) (movement of drugs through the body) and pharmacodynamics (PD) (biological response) which is generally known as (PK-PD dynamics). The PK-PD relationship can be described mathematically using various models, and these models can be used to predict the pharmacological response to a drug based on its PK profile. The emphasis of the project will be to produce software tools that accelerate scientific research in this area by considering how scientists (drug developers) use and interact with existing and novel PK-PD models.
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