Research Culture of Practice-Based Research Networks

描述(由申请人提供)：初级保健研究越来越多地在以实践为基础的研究网络(PBRN)内进行。虽然基于社区的研究提供了更好的外部有效性的优势，但它也带来了挑战，包括实施标准化的研究方案，以及培训和监测诊所工作人员中负责任的研究行为(RCR)实践。关于PBRN对RCR标准的遵守情况以及与研究诚信相关的研究专业精神的其他方面(即“研究文化”)，人们知之甚少。该项目的目标是为PBRN制定一份研究专业精神检查表，以自我评估其当前的研究文化。该项目有可能改善PBRN的研究文化，鼓励PBRN优先开展能够加强其组织的研究专业性的活动。传播将包括根据具有最高自我评估的PBRN的经验提出的政策和标准作业程序。该项目的具体目标如下：目标1：为PBRN研究专业精神问卷生成项目，解决医学研究所确定的研究完整性知识库中的不足之处。目的2：建立问卷的内容效度。目标3：开发具有良好心理测量学特征的研究专业精神检查表。目标4：开展一项全国性调查，以确定PBRN研究的专业性。项目需求：这项研究的目的是解决医学研究所和研究诚信办公室确定的与研究完整性相关的知识库中的不足之处。公共卫生影响：通过促进PBRN研究的专业性；该项目应该有助于提高公众参与能够建立初级保健证据基础的研究的意愿。创新和影响：通过开发一种特定于PBRN的研究诚信政策和做法模式，网络可以用来自我评估其研究文化并设定改进目标，从而增强以实践为基础的研究的潜力。该项目的一个具体成果将是研究专业精神检查表，它根据作为项目一部分建立的标准，导致获得作为“专业”PBRN的资格。该项目将促进PBRN发展成为成熟的专业研究组织，具有促进研究诚信和负责任的研究行为的标准。印第安纳大学PBRN资源中心和韦恩州立大学实践研究部的一组调查人员将合作确保该项目的成功。

DESCRIPTION (provided by applicant): Primary care research is increasingly conducted within practice-based research networks (PBRNs). While community-based research offers the advantage of greater external validity, it also presents challenges that include implementing standardized research protocols, and the training and monitoring of responsible conduct of research (RCR) practices among clinic staff. Little is known about PBRN adherence to standards of RCR, and other aspects of research professionalism that relate to research integrity (i.e. "research culture"). The project objective is to develop a Research Professionalism Check-list for PBRNs to self- assess their current research culture. This project has the potential to improve PBRN research culture by encouraging PBRNs to prioritize activities that strengthen the Research Professionalism of their organization. Dissemination will include suggested policies and standard operating procedures based on the experiences of the PBRNs with the highest self-assessment. The specific aims of the project are as follows: Aim 1: Generate items for a PBRN Research Professionalism questionnaire that address the areas of deficiency in the research integrity knowledge base identified by the Institute of Medicine. Aim 2: Establish content validity of the questionnaire. Aim 3: Develop Research Professionalism Checklist with sound psychometric attributes. Aim 4: Conduct a national survey to determine PBRN research professionalism. Need for Project: The study aims are constructed to address areas of deficiency in the knowledge base related to research integrity identified by the Institute of Medicine, and the Office of Research Integrity. Public Health Implication: By promoting PBRN research professionalism; this project should contribute to greater public willingness to participate in research that can build the evidence-base of primary care. Innovation and Impact: The potential of practice-based research would be enhanced by developing a PBRN-specific model of research integrity policies and practices that networks can use to self-assess their research culture and set goals for improvement. A tangible product from this project will be the Research Professionalism Check-list, which leads to a qualification as a "professional" PBRN according to criteria established as part of the project. This project will promote the development of PBRNs into mature professional research organizations with standards that promote research integrity, and the responsible conduct of research. A team of investigators from the PBRN Resource Center at Indiana University, and the Wayne State University Division of Practice-based Research will collaborate to ensure the success of the project.