Aeroacoustics of Voice

描述（由申请人提供）：本研究的长期目标是建立广泛、准确和可靠的发声理论，有助于建立完善和适用的概念和方法来帮助有声音问题的人。这一目标必须发展、使用和完善广泛有效的发声模型，并量化控制喉部功能和声音质量的生物力学、空气动力学和声学因素。本应用程序的目的是建立对声带振荡、半喉发声、音域移位和声带冲击动力学的生物力学、运动学、空气动力学和声学的牢固理解。这一目标将通过实验和计算方法的独特结合来实现。在本研究中，将使用三种互补模型的创新组合。这三种模型分别是：切除喉模型、机械喉模型和有限元生物物理模型。这项工作的结果不仅将增强我们对正常发声的理解，而且将阐明声带病变是如何发展的，以及声带麻痹等疾病是如何破坏声带振动的，这反过来可以为改进声音障碍的手术和行为治疗提供见解。本次资助期的具体目标是：(1)建立解耦声带振荡的控制机制；(2)建立半咽振荡的最佳条件；(3)建立胸音和假声转换的控制机制；(4)建立影响潜在破坏性动压力和组织内外应力的生物力学和空气动力学因素。本研究项目的结果将对发声中的重要问题提供重要的指导和理解，即声带振荡的控制、半喉发声、音域转换以及对声带潜在的破坏性冲击力。

DESCRIPTION (provided by applicant): The long-range objective of this research is to establish broad range, accurate, and reliable theories about phonation that can be useful in establishing refined and applicable concepts and approaches for helping people with voice problems. This goal, of necessity, must develop, use, and refine widely effective models of phonation, and quantify the biomechanical, aerodynamic, and acoustic factors that control laryngeal function and voice quality. The objective of this application is to establish a firm understanding of the biomechanics, kinematics, aerodynamics, and acoustics of vocal fold oscillation, hemilarynx phonation, register shift, and vocal fold impact dynamics. This objective will be met through a unique combination of experimental and computational methods. In this research, an innovative combination of three complimentary models will be used. The three models are: excised larynx model, a mechanical larynx model, and a finite-element biophysical model. The results of this work will not only enhance our understanding of normal phonation, but will elucidate how vocal lesions develop and how disorders such as vocal fold paralysis disrupt vocal fold vibration, which in turn could provide insight into improved surgical and behavioral treatment of voice disorders. The specific aims for this funding period are: (1) To establish the control mechanisms for decoupling vocal fold oscillation; (2) To establish optimal conditions for hemilarynx oscillation; (3) To establish the control mechanisms for transition between chest and falsetto registers; and (4) To establish the biomechanical and aerodynamic factors that influence the potentially damaging dynamic pressures and internal and external tissue stresses. The outcome of this research project should provide significant guidance and understanding of important issues in phonation, namely, the control of vocal fold oscillation, hemilarynx phonation, register transition, and potentially damaging impact forces on the vocal fold.