A 3-D Interactive Atlas of the Maxilla, Mandible & TMJ

描述：该项目将产生具有一定分辨率的解剖结构模型，由于技术限制，这在以前是不可能的。可见人类项目（VHP）是第一个使用连续横截面来构建体素模型的演示。虽然VHP代表了一个里程碑式的努力，但它受到样本量有限，（两个主题），分辨率和分割问题的困扰。该项目将增加样本量，并以更高的分辨率收集数据。然后，它将集中在一个特定的解剖部分-颞下颌关节，以说明正常和异常的解剖样本，并演示关节的功能运动。第一个目标是定义上颌骨、下颌骨、颞下颌关节和周围组织的解剖、血管、神经支配、肌肉和骨骼。我们将使用在第一阶段拨款期间完善的数据收集方法。查看协议将被扩展，允许我们分割、移除和替换各种结构。为了更好地了解解剖结构，我们将把CT、MRI和数码摄影数据联系起来。所有的模型都是完全互动的，可以围绕六个轴旋转，有注释，可以分段关闭和打开，并可以立体观看。第二个目的是通过包含来自UCSF的重要头骨收集的扫描数据来说明TMJ的病理。第三个目标是开发一个全面的TMJ地图集。它将包括关节的宏观解剖包括关节囊解剖，神经支配，血管分布和咀嚼相关肌肉。观众将能够通过其所有的运动来移动注释关节，并观察肌肉组织如何在咀嚼和下颌运动中工作。以高分辨率成像解剖小离散区域的能力提供了有用的数据，是教育和临床有用的，是一个全面的高分辨率库的重要贡献。该地图集将供医学和牙科学生、口腔颌面外科医生、放射科医生、整形外科医生和耳鼻喉外科医生使用。

DESCRIPTION: This project will produce models of anatomical structures with a degree of resolution that, because of technological limitations, has not been previously possible. The Visible Human Project (VHP) was the first demonstration of the use of serial cross sections to build voxel models. While the VHP represent a landmark effort, it suffers from limited sample size, (two subjects), resolution and segmentation problems. This project will increase the sample size and will collect data at a dramatically higher resolution. It will then concentrate on a specific piece of anatomy - the TMJ, to illustrate normal and abnormal anatomical samples and to demonstrate the functional movements of the joint. The first Aim is to define the anatomy, vascularity, innervation, muscle, and bone of the maxilla, mandible, TMJ and surrounding tissue. We will use data collection methods perfected during the Phase I grant. Viewing protocols will be expanded, allowing us to segment, remove and replace various structures. Ancillary to this, we will correlate the CT, MRI and digital photographic data for a better understanding of the anatomy. All of the models will be fully interactive, rotatable around six axes, annotated, capable of being turned off and on segmentally and viewed in stereo. The second Aim is to illustrate the pathology of the TMJ by the inclusion of scanned data of an important collection of skulls from UCSF. The third Aim is to develop a comprehensive Atlas of the TMJ. It will include the macroanatomy of the joint including the capsular anatomy, innervation, vascularity and the associated muscles of mastication. The viewer will be able to move the annotated joint through all of its movements and observe how the musculature works in both mastication and mandibular movements. The ability to image small discrete areas of anatomy at high resolution provides useful data that is educational and clinically useful and is an important contribution to a comprehensive high-resolution library. The Atlas will be designed to be used by medical and Dental students, oral and maxillofacial surgeons, radiologists, plastic and ENT surgeons.