RENOVATIONS FOR CAGEWASH SUPPORT SERVICE

描述（由申请方提供）：本项目的总体目标是升级和扩展斯托尼布鲁克大学（SBU）实验动物资源部健康科学中心设施饲养的实验动物的笼洗支持服务。该机构有短期和长期目标，以改善动物护理和服务，以支持研究计划。35个基础和临床应用实验室，从事基因识别、绘图、分析和调节研究;细菌和病毒受体调节;靶向基因治疗;传染病发病机制;肿瘤学;脑淀粉样血管病;疫苗开发;和膜运输，目前在健康科学中心设施内饲养动物。无病原体啮齿动物种群的急剧增加促使需要额外的笼清洗设备（隧道清洗机）来维持动物护理卫生方案。现有的18岁机架洗衣机是失败的，需要更换。需要一个新的辅助HVAC系统来支持新设备，以保持AAALAC标准。扩大笼舍清洗支持区域将改善工作流程，降低动物相关成本，并保护动物护理人员免受职业相关伤害。这笔赠款将购买一个隧道洗衣机，机架洗衣机和补充暖通空调系统。设备和HVAC安装需要对现有笼清洗支持区域进行翻新。新设备和笼清洗支持区域的扩展对于满足支持扩大无病原体啮齿动物种群、维持健康的大型动物群体以及通过升级现有设施降低动物护理人员的职业健康风险的巨大计划需求至关重要。

DESCRIPTION (provided by applicant): The general objective of this project is to upgrade and expand cagewash support services for laboratory animals housed in the Health Sciences Center facility in the Division of Laboratory Animal Resources at Stony Brook University (SBU). The institution has both short term and long term goals to improve animal care and services to support the research program. 35 basic and clinically applied laboratories, who conduct research in gene identification, mapping, analysis and regulation; bacterial and viral receptor regulation; targeted gene therapy; infectious disease pathogenesis; oncology; cerebral amyloid angiopathy; vaccine development; and membrane transport, currently house animals within the Health Sciences Center facility. The dramatic increase in pathogen free rodent populations drives the need for additional cagewashing equipment (tunnel washer) to maintain animal care sanitation protocols. An existing 18 year old rack washer is failing and needs replacement. A new supplemental HVAC system is required to support the new equipment to maintain AAALAC standards. Expansion of the cage washing support area will improve work flow, reduce animal related costs and safeguard animal care staff from occupational related injury. The grant will purchase a tunnel washer, rack washer and a supplemental HVAC system. Renovations in existing cage wash support area is required for equipment and HVAC installation. New equipment and expansion of the cage wash support area is essential to meet the dramatic programmatic need to support expanding pathogen free rodent populations, maintain healthy large animal colonies and reduce occupational health risks for animal care personnel through upgrade of existing facilities.