短期课程：综合和器官系统药理学-猫眼课题宝

短期课程：综合和器官系统药理学

批准号：

7232109

负责人：

DAVID B BYLUND

金额：

$17.46万

依托单位：

UNIVERSITY OF NEBRASKA MEDICAL CENTER

依托单位国家：

美国

项目类别：

财政年份：

2005

资助国家：

美国

项目状态：

已结题

起止时间：

2005-05-01 至 2009-04-30

来源：

https://reporter.nih.gov/project-details/7232109

关键词：

Academia Academic Medical Centers Academy Accreditation Acepromazine Acetaminophen #3 Action Potentials Acute Address Adhesives Adolescent Adrenergic Receptor Adult Adverse effects Advisory Committees Affect Affinity Age Agonist Algorithms American Amyloid deposition Analgesics Anatomy Anesthesia procedures Anesthetics Angiotensin II Anhedonia Animal Behavior Animal Experimentation Animal Husbandry Animal Model Animal Organ Animal Technicians Animal Welfare Animals Anti-Arrhythmia Agents Anti-Inflammatory Agents Anti-inflammatory Antibiotics Anticonvulsants Antidepressive Agents Antiepileptic Agents Antipsychotic Agents Aorta Appendix Apple Area Arkansas Arrhythmia Arteries Arts Atropine Attention Autacoids Autonomic Agents Award B 31 Baroreflex Bathing Behavior Behavioral Behavioral Research Biochemical Bioinformatics Biological Biological Models Biological Sciences Biomedical Research Biophysics Birth Blood Blood Circulation Blood Platelets Blood Pressure Blood Pressure Monitors Blood Vessels Blood Volume Blood capillaries Blood drug level result Blood flow Blood specimen Boxing Brain Bread Breeding Buffers Calcium Canis familiaris Carbon Dioxide Cardiac Cardiac Glycosides Cardiac Myocytes Cardiac Output Cardiology Cardiovascular Agents Cardiovascular Physiology Cardiovascular system Caring Carotid Body Catalepsy Categories Catheters Cavia Cell Nucleus Cells Cephalic Cerebrum Chairperson Characteristics Chemicals Chemosensitization Chest Chicago Chronic Citalopram Cities Class Clinic Clinical Clinical Research Clinical Trials Cognition Cognitive deficits Colorado Commit Companions Complex Computational Molecular Biology Computer Assisted Condition Conscious Consensus Continuing Education Contracts Control Groups Coronary Coronary artery Daily Data Data Collection Dental Societies Dental Students Dependovirus Depth Desipramine Detection Development Developmental Disabilities Devices Diabetes Mellitus Dietary Cholesterol Dietary Intervention Digitalis (genus)Digitalis Glycosides Digitalis preparation Disadvantaged Discipline Disease Distress Doctor of Philosophy Dopamine Receptor Dose Drug Administration Routes Drug Delivery Systems Drug Evaluation Drug Industry Drug Kinetics Drug Receptors Drug effect disorder Drug usage EFRAC Echocardiography Education Educational Activities Educational process of instructing Educational workshop Electrocardiogram Electronic Mail Electroporation Employee Employment Employment Opportunities End Point Endothelium Ensure Environment Enzymes Epithelial Esthesia Ethics Ethnic Origin Euthanasia Evaluation Evaluation Research Event Exclusion Exercise Experimental Designs Experimental Models Exposure to Extinction (Psychology)Extracellular Space Faculty Failure Family suidae Fatty Acids Feeling Fees Felis catus Fluorescence Focus Groups Food Food Services Formalin Fostering Foundations Foxes Freund&apos s Adjuvant Funding Future Gases Gender Gene Transfer Genetic Genetically Modified Organisms Genomics Gland Glaucoma Glomus Cell Glutamates Goals Government regulations Graduate Education Grant Graph Group Meetings Guidelines Hand Health Heart Heart Rate Heart failure Heating Heterogeneity Histamine H3 Receptors Histamine Receptor Hormones Housing Human Hyperalgesia IACUC Ibuprofen Image Imagery Imaging Techniques Impaired cognition Implant Implantation procedure In Situ In Vitro Incubated Individual Industry Infarction Infection Inflammation Information Centers Infusion procedures Injection of therapeutic agent Injury Institutes Institution Instruction Insulin-Dependent Diabetes Mellitus Internal Medicine International Internet Internships Intraperitoneal Injections Intravenous Invasive Investigation Ion Channel Iowa Ireland Ischemia Isoflurane Isoproterenol Joint Ventures Joints Journals Kansas Ketamine Kidney Kinetics Knowledge Laboratories Laboratory Animal Medicine Laboratory Animal Models Laboratory Animals Laboratory Research Lactation Lead Leadership Learned Helplessness Learning Legal patent Length Lesion Letters Leukocytes Licensing Life Ligands Ligation Light Lipids Logistics Lysophospholipids Mails Maintenance Mammals Manuscripts Marketing Measurement Measures Mechanics Mediating Medical Medical Education Medical Students Medical center Medicine Membrane Potentials Memory Mental Depression Mental Retardation Mental disorders Mentors Mesentery Messenger RNA Metabolic Pathway Metabolism Methods Microcirculation Microdialysis Microinjections Microscopic Minnesota Minor Surgical Procedures Minority Mission Missouri Modeling Molecular Molecular and Cellular Biology Monitor Monkeys Monoamine Oxidase Inhibitors Morphine Motor Motor Activity Mouse Strains Movement Multimedia Mus Muscle Cells Muscle function Myocardial Myocardial Infarction Myocardium Myron N-Methylaspartate Names National Institute of General Medical Sciences National Research Council Nature Nebraska Neonatal Nerve Nerve Degeneration Nervous System Physiology Nervous system structure Neuraxis Neurobiology Neuropharmacology Neurosciences Neurosciences Research Neurotransmitters New York Nitric Oxide Nociception Norepinephrine North Dakota Numbers Oklahoma Online Systems Opening of the Thorax Operative Surgical Procedures Ophthalmology Opioid Organ Organism Oryctolagus cuniculus Ouabain Outcome Oxidants Oxidation-Reduction Oxygen Oxytocin Pain Pain Research Pamphlets Participant Patient currently pregnant Pattern Peptides Perception Performance Peripheral Peripheral Nervous System Permeability Personal Satisfaction Persons Pharmaceutical Preparations Pharmacologic Substance Pharmacology Pharmacology and Toxicology Pharmacy facility Phase Phenobarbital Phenotype Phospholipids Phosphorylation Physical Restraint Physical therapy Physiologic Intraocular Pressure Physiological Physiological Processes Physiological reperfusion Physiology Pilocarpine Pilot Projects Placement Plasma Policies Population Positioning Attribute Postdoctoral Fellow Postoperative Period Pregnancy Preparation Price Primates Principal Investigator Procedures Process Production Program Research Project Grants Property Proteins Protocols documentation Psychiatry Psychology Publications Publishing Purpose Qualifying RNA Race Randomized Range Rate Rattus Receptor Cell Recommendation Recording of previous events Recovery Recruitment Activity Reflex action Regulation Regulatory Affairs Renal function Reperfusion Therapy Reporting Research Research Activity Research Design Research Personnel Resistance Resources Respiration Respondent Rest Restaurants Review Committee Right atrial structure Risperidone Rodent Rodent Model Role Rompun Route Running Safety Saline Salivary Salivary Glands Schedule Schizophrenia Science Scientist Scopolamine Screening procedure Secure Seizures Selective Serotonin Reuptake Inhibitor Self Administration Sensory Services Sheep Short-Term Memory Signal Transduction Signal Transduction Pathway Site Skin Small Intestines Smooth Muscle Smooth Muscle Myocytes Social Welfare Social Work Societies Solutions Source South Dakota Specific qualifier value Sprague-Dawley Rats Staining method Stains Standards of Weights and Measures Stem cells Sterility Sterilization for infection control Stimulus Stress Structure of jugular vein Structure of submaxillary duct Students Surgical Instruments Surgical sutures Surveys Sus scrofa Swimming Symptoms System Teaching Hospitals Techniques Telefacsimile Telemetry Telephone Temperament Temperature Terminology Testing Therapeutic Therapeutic Effect Therapeutic Index Thoracotomy Time Tissue Harvesting Tissues Title Toxicology Training Training Programs Training Support Tranquilizing Agents Transfection Transgenic Animals Transgenic Mice Translational Research Transportation Travel Trust Ultrasonography Uncertainty Uninsured Medical Expense United States Department of Veterans Affairs United States National Institutes of Health Universities Utah Variant Vascular Endothelial Growth Factors Vascular Smooth Muscle Vasopressins Vendor Venous Vertebrates Veterinarians Videotape Virginia Visceral Voting Wages Walking Washington Water Week Weight Gain Whole Organism Withdrawal Work Writing Zoonoses absorption allodynia animal care animal facility antiglaucoma drug arteriole base behavior measurement behavior observation behavioral sensitization biobehavioral measurement body system capillary cardiovascular pharmacology career celecoxib chronic neuropathic pain clinically relevant college comparative concept cost cremaster muscle day design dopamine D3 receptor dopamine system drinking water drug development drug discovery drug distribution drug metabolism drug reinforcement drug seeking behavior drug testing ectoATPase editorial egg expectation experience experimental analysis follow-up foot gabapentin hemodynamics human subject implantable device impression improved in vivo in vivo Model indexing inhibitor/antagonist instructor instrument instrumentation interest investigator training killings knowledge base lamotrigine lectures left coronary artery lysophosphatidic acid male medical schools member mesangial cell metabolic abnormality assessment microwave electromagnetic radiation neuropsychiatry novel papillary muscle patch clamp payment peer postcapillary venule pre-clinical pre-clinical research pre-doctoral preconditioning pressure professor programs psychostimulant receptor renal ischemia research and development research study response reuptake sex size sound species difference success symposium systems research theories uptake vascular bed vascular inflammation venule vision science

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中文摘要

翻译

描述（由申请人提供）：拟议的综合和器官系统药理学短期课程旨在为研究生，博士后，初级教师和工业科学家提供讲座，演示和实践经验与整个动物。随着越来越多的药理学培训课程在本质上完全是细胞和分子的，这已经成为一个越来越重要的问题。该课程将在夏季提供两周以上，重点是心血管和神经药理学。将提供有关IACUC的功能，动物的人道待遇和法规的讲座，心血管生理学，药理学和神经药理学的背景材料。将使用仪器动物（犬、兔）进行整体动物心血管实验，并将使用各种技术检查啮齿动物的伤害感受和认知。分离的血管材料和心脏将用于器官系统研究。这些实验中使用的药物将与仪器动物中使用的药物相同。也将有1.5天留出选修，动手，由学生选择的重点经验。有兴趣的学生可以选择第三周的实习。

英文摘要

DESCRIPTION (provided by applicant): The proposed Short Course in Integrative and Organ Systems Pharmacology is designed to provide graduate students, postdocs, junior faculty and industrial scientists with lectures, demonstrations and hands on experiences with whole animal. This has become an issue of increasing importance as more and more pharmacology training programs have become exclusively cellular and molecular in nature. The course to be offered over two weeks in the summer will focus on cardiovascular and neuropharmacology. Lectures will be provided on the functioning of IACUCs, the humane treatment of animals and regulations appropriate to this, background material on cardiovascular physiology, pharmacology and neuropharmacology. Instrumented animals will be used (dogs, rabbits) for whole animal cardiovascular experiments and various techniques will be used for examining nociception and cognition in rodents. Isolated vascular material and hearts will be used for organ system studies. The drugs used in these experiments will be the same as those used in the instrumented animals. There will also be 1.5 days set aside for elective, hands on, focused experiences selected by the students. An optional third week internship will be available for interested students.

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