VIIth International Conference on Brain Energy Metabolism

第七届国际脑能代谢会议：“神经元-神经胶质相互作用的分子、细胞和代谢方面的整合”，将于2006年8月15日至18日在瑞士洛桑联邦理工学院举行。通常认为，大脑能量代谢本身并不是一门学科；相反，它位于其他几个研究领域的交汇处。其中包括疾病相关研究（中风、帕金森氏病、亨廷顿氏病、糖尿病等）、体内和亚细胞成像技术（PET、MRS、荧光原位成像、质量同位素方法）、胶质神经元相互作用、代谢组学和线粒体生理学。这次会议的主要目的是在一个非常互动的论坛中，汇集来自这些不同领域的研究人员，否则他们就不会在这种环境中互动。有30位受邀演讲者，预计出席人数约为100人。会议将包括葡萄糖-糖原代谢的调节，体内细胞氧化还原电位成像，线粒体在兴奋性毒性和疾病中的作用，谷氨酸传递和体内平衡的新方面，与脑能量学相关的体内和亚细胞成像模式，代谢控制分析和代谢组学。受邀的演讲者既有资深调查人员，也有初级调查人员。此外，还将从提交的摘要中选择几次学生/博士后“数据闪电战”。该系列的过去会议非常成功，导致来自不同领域和地区的研究人员之间的热烈讨论和研究合作。每一次会议都有不同的重点，以配合这一领域不断发展的方面，每一次会议都产生了被高度引用的会议记录。资金将部分用于支付受邀演讲者的旅费和住宿费，并为优秀的研究员和研究生提供支持。已经为会议建立了一个网站。

DESCRIPTION (provided by applicant): Support is requested for the Seventh International Conference on Brain Energy Metabolism: "Integrating Molecular, Cellular, and Metabolic Aspects of Neuron-Glia Interactions", to be held August 15-18, 2006 at the Ecole Polytechnique Federale de Lausanne, Switzerland. Brain energy metabolism is not generally recognized as a discipline per se; rather, it lies at the confluence of several other research areas. These include disease related research (stroke, Parkinson's disease, Huntington's disease, diabetes, others), in vivo and subcellular imaging technologies (PET, MRS, fluorescence in-situ imaging, mass isotopomer approaches), glial-neuron interactions, metabolomics, and mitochondrial physiology. The primary aim of this conference is to bring together, in a very interactive forum, investigators from these different fields who would not otherwise interact in this type of setting. There are 30 invited speakers and an anticipated attendance of about 100. Meeting sessions will include sessions on regulation of glucose-glycogen metabolism, imaging the cellular redox potential in vivo, mitochondrial roles in excitotoxicity and disease, novel aspects of glutamate transmission and homeostasis, in vivo and subcellular imaging modalities germane to brain energetics, metabolic control analysis and metabolomics. The invited speakers are a mix of established and junior investigators. There will in addition be several student/postdoc "data blitzes" selected from submitted abstracts. Past meetings in this series have been extremely successful, leading to lively discussions and research collaborations between investigators from disparate fields and regions. Each of these meetings has had a different focus, in line with the evolving aspects of this field, and each has generated highly cited meeting proceedings. Funds will be used to partially defray the travel & lodging costs of invited speakers, and to provide support for meritorious fellows and graduate students. A website for the conferences has been established.