Developing novel scaffold proteins to stabilize and enhance protein-based insecticides

这个CASE应用程序是Plevin、Spicer和先正达之间的新合作，建立在之前BBSRC资助的研究（BB/T012013/1）的基础上。该学生将主要在约克的普列文小组学习。所得蛋白靶点的生物物理特性的表征将与plevin一起进行，并将采用相关的生化、生物物理和结构技术。学生将花大量的时间在Spicer实验室，在那里他们将获得蛋白质的化学修饰和使用非天然氨基酸技术来修饰蛋白质功能的专业知识。

This CASE application is a new collaboration between Plevin, Spicer andSyngenta that builds on previous BBSRC funded research (BB/T012013/1).The student will be largely based in the Plevin group in York. Characterisationof the biophysical properties of resulting protein targets will be conducted withPlevin and will employ relevant biochemical, biophysical and structuraltechniques. The student will spend significant time in the Spicer Lab wherethey will gain expertise in chemical modification of proteins and the use ofnon-native amino acids technologies to modify protein function.