Tulane/LSU HIV/AIDS Clinical Trials Networks Unit

描述（由申请人提供）：杜兰大学/路易斯安那州立大学艾滋病毒/艾滋病临床试验单位（CTU）将设在一个单一的机构，新奥尔良路易斯安那州医疗中心（MCLNO），正式名称为新奥尔良慈善医院。CTU代表了杜兰大学和路易斯安那州立大学健康科学中心之间的合作努力。这两个医疗中心都利用MCLNO作为他们的主要教学医院，两所学校在MCLNO的艾滋病毒治疗和研究项目方面有着悠久的合作历史。CTU由两个临床研究站点（CRS）组成，一个是孕产妇/儿童临床研究站点，一个是成人临床研究站点。孕产妇/儿童CRS代表目前的儿科艾滋病临床试验单位。母婴服务中心隶属于影响行动网络，已被选为其最喜欢的十个国内站点之一。它将侧重于影响行动网络正在处理的四个优先领域：(1)疫苗研究与开发；(2)转化研究和药物开发；(3)优化临床管理，包括合并症；(4)预防艾滋病毒母婴传播。孕产妇/儿童研究报告具有在母婴传播、感染艾滋病毒的青少年和艾滋病毒行为方面的专门知识，为影响行动计划带来了对太平洋行动计划作出科学贡献的悠久历史。成人艾滋病临床试验中心由前杜兰大学/路易斯安那州立大学成人艾滋病临床试验中心组成。它不隶属于一个网络，将专注于一个优先领域：转化研究和药物开发。成人CRS非常适合解决这一重要的优先领域，可以接触到大量的住院和门诊艾滋病毒患者，使用杜兰大学/路易斯安那州立大学综合临床研究中心，以及药理学、药物开发、逆转录病毒学、妇女健康和机会性感染（包括结核病、丙型肝炎病毒和HPV）方面的专业知识。CTU将进行由IMPAACT网络和成人网络开发的临床试验，以开发新的和改进的方法来治疗和预防成人和儿童的艾滋病毒感染。

DESCRIPTION (provided by applicant): The Tulane/LSU HIV/AlDS Clinical Trials Unit (CTU) will be based in a single institution, The Medical Center of Louisiana in New Orleans (MCLNO), formally known as Charity Hospital of New Orleans. The CTU represents a collaborative effort between the Tulane and Louisiana State University Health Sciences Centers. Both medical centers utilize the MCLNO as their primary teaching hospital and there is a long history of collaboration between the two schools in HIV treatment and research programs based at MCLNO. The CTU is comprised of two clinical research sites (CRS), a Maternal/Child CRS and an Adult CRS. The Maternal/Child CRS represents the current Pediatric AIDS Clinical Trials Unit. The Maternal/Child CRS is affiliated with the IMPAACT Network, having been selected as one of its ten highly preferred domestic sites. It will focus on the four priority areas being addressed by the IMPAACT Network: (1) Vaccine Research and Development; (2) Translational Research and Drug Development; (3) Optimization of Clinical Management, Including Co-Morbidities; and (4) Prevention of Mother-to-Child Transmission of HIV. The Maternal/Child CRS brings to IMPAACT a strong history of scientific contribution to the PACTG with expertise in maternal-to-child transmission, the HIV-infected adolescent and behavioral aspects of HIV. The Adult CRS consists of the former Tulane/LSU Adult AIDS Clinical Trials Unit. It is not affiliated with a network and will focus on one priority area: Translational Research and Drug Development. The adult CRS is ideally suited to address this important priority area with access to a large inpatient and outpatient population of HIV patients, use of the Tulane/LSU General Clinical Research Center, and expertise in pharmacology, drug development, retrovirology, woman's health, and opportunistic infections including tuberculosis, hepatitis C virus, and HPV. The CTU will conduct clinical trials developed by the IMPAACT Network and an Adult Network in order to develop new and improved ways to treat and prevent HIV infection in adults and children. ADMINISTRATIVE COMPONENT: