2007 Gradient Sensing & Directed Cell Migration GRC

描述(申请人提供)：第二届戈登梯度传感和定向细胞迁移会议将于2007年1月28日至2月2日在加利福尼亚州文图拉的皇冠假日酒店举行。这次会议将直接聚焦于真核细胞趋化的机制。由于趋化性对过敏和传染病、神经疾病、发育、免疫学、伤口愈合和肿瘤细胞转移至关重要，此次会议旨在将这些领域的领先趋化性研究人员聚集在一起，相互交流概念和方法。这一策略通过在过程中按阶段组织每个主题来体现；例如，专注于趋化信号网络的不同领域的研究人员被聚集在一次会议中。选择会议主题是为了将注意力集中在趋化信号的关键步骤上，为与会者提供整个会议过程中整个趋化过程的综合概述。这次会议的目的是通过将建模人员与领先的专家聚集在一起，研究白细胞、神经元、成纤维细胞、肿瘤细胞、酵母、网状网壳和果蝇等系统中的趋化作用中的细胞极化，从而促进我们对这些机制的理解。我们计划举行九次会议，举行大约34次全体会议，每一次会议将由一名这一专题的专家主持，他将领导讨论。计划了相当长的时间来鼓励广泛的讨论。该计划将为各级研究人员提供参与的机会，包括那些目前由NIH资助的研究人员，包括NIGMS、NINDS、NHLBI、NICHD、NCI和NIAID。该方案还将提供10次“短谈”演讲的机会，由各届会议主席从提交的摘要和海报中挑选。最后选定的与会者名单(包括会议主席、发言者和与会者)将代表所有部门的研究人员。我们将鼓励初级调查人员、博士后见习人员和新的调查人员参加会议的方方面面。此外，我们将促进妇女、不同的少数群体和残疾人士对趋化作用的研究感兴趣。

DESCRIPTION (provided by applicant): The second Gordon Conference on Gradient Sensing and Directed Cell Migration will be held January 28 - February 2, 2007 at the Crowne Plaza, Ventura, California. This meeting will focus directly on mechanisms of eukaryotic chemotaxis. Because chemotaxis is critical for allergies and infectious disease, neurological diseases, development, immunology, wound healing, and tumor cell metastasis, the meeting is designed to bring together the leading chemotaxis researchers in these fields for cross-fertilization of concepts and approaches. This strategy is manifested by organizing each topic according to stage in the process; for example, researchers in different fields who are focused on chemotaxis signaling networks are grouped together in a single session. The session topics are chosen to focus attention on the critical steps in chemotactic signaling, providing attendees with an integrated overview of the entire chemotaxis process over the course of the entire meeting. The goal of the meeting is to advance our understanding of these mechanisms by bringing together modelers with the leading experts in the study of cell polarization in chemotaxis in systems including leukocytes, neurons, fibroblasts, tumor cells, yeast, Dictyostelium, and Drosophila. We have planned nine sessions with roughly 34 plenary talks, and each session will be chaired by an expert in the topic who will lead the discussion. Considerable time is planned to encourage extensive discussion. The program will provide opportunities for investigators at all levels to participate, including those currently funded through the NIH, including NIGMS, NINDS, NHLBI, NICHD, NCI, and NIAID. The program will also provide opportunity for 10 "short talk" presentations, which will be selected by the session chairs from submitted abstracts and posters. The final list of conferees (including session chairs, speakers and participants) will be chosen so as to represent researchers from all sectors. We will encourage the participation of junior investigators, post-doctoral trainees and new investigators to the field in all aspects of the meeting. In addition, we will foster the involvement of women, diverse groups of minorities and handicapped individuals who are interested in studying chemotaxis.