NEMCH Clinical Research on AIDS Training Grant

描述(由申请人提供)：这份由塔夫茨-新英格兰医学中心地理医学和传染病部门(GMID)提供的艾滋病临床培训补助金的竞争性续签提案是作为布朗大学医学院/米里亚姆医院艾滋病毒项目的互动项目提交的。我们的目标是继续对研究人员进行艾滋病毒/艾滋病临床研究方法方面的培训，重点强调这两个项目各自的独特优势。这些问题包括：艾滋病毒中的营养和代谢问题、艾滋病毒中的特殊人群(包括妇女、少数民族、注射吸毒者和被监禁人群)、结果研究和决策分析、国际艾滋病研究以及艾滋病毒/艾滋病临床研究(包括位于布朗大学的艾滋病临床试验单位以及基于我们自己的基本艾滋病毒/艾滋病研究计划的研究)。通过教授核心方法以及学员在经验丰富和能干的导师的监督下设计和进行的指导临床研究，我们预计将培训下一代艾滋病临床研究人员，使他们的工作和培训补助金的工作将直接影响和改善艾滋病毒感染者的临床实践和结果。我们要求每年提供3个资助职位；每个学员都可以选择一个临床研究学位项目，也可以进行一个有指导的研究项目。对学员的教学培训，无论他们是否选择学位课程，都将强调研究设计中的基本方法论。这笔培训补助金的教职员工资金非常充足，许多教职员工通过艾滋病研究中心(CFAR)、亚洲艾滋病毒福格蒂培训计划和艾滋病毒与营养计划项目等形式进行着持续的、富有成效的合作。通过导师制度、补助金执行委员会(包括两所院校的教师)和每位学员的研究协调委员会(再次包括两所院校的教师)，我们打算为每位学员提供个性化和最优化的培训机会。广泛的评估过程，包括书面报告和向培训补助金全体教职员工介绍研究结果，将确保每个受训人员在其职业发展中得到充分支持，并充分利用所提供的培训机会的深度和广度。

DESCRIPTION (provided by applicant): This competitive renewal proposal for an AIDS Clinical Training Grant from the Division of Geographic Medicine and Infectious Diseases (GMID) at the Tufts-New England Medical Center is submitted as an interactive program with the Brown University School of Medicine/Miriam Hospital HIV program. Our goal is to continue to train investigators in methods of HIV/AIDS clinical research with an emphasis on the unique strengths of the two programs individually. These include: nutritional and metabolic issues in HIV, special populations in HIV including women, ethnic minorities, injection drug users, and incarcerated populations, outcomes research and decision analysis, international AIDS research, and clinical studies in HIV/AIDS including an AIDS Clinical Trial Unit based at Brown and those based on our own basic HIV/AIDS research programs. By teaching core methods together with mentored clinical research designed and carried out by trainees under the supervision of experienced and able mentors, we expect to train the next generation of AIDS clinical investigators to a level competitive for independent funding, so that their work and the work of the training grant will have a direct impact on and improve clinical practice and outcomes in HIV infected patients. We have requested 3 funded positions per year; each trainee has the option of electing a degree program in clinical research as well as conducting a mentored research project. Didactic training for trainees, whether they select a degree program, will emphasize basic methodology in study design. The faculty for this training grant is exceptionally well funded and many of the faculty have ongoing, productive collaborations in the form of a Center for AIDS Research (CFAR), a Fogarty Training Program in HIV for Asia and a Program Project in HIV and Nutrition. Through the mentoring system, the Executive Committee of the Grant, which included faculty from both institutions, and each trainee's Research Coordination Committee, again including faculty from both institutions, we intend to individualize and optimize training opportunities for each trainee. An extensive evaluation process, including written reports and presentation of research results to the whole faculty of the training grant will ensure that each trainee is fully supported in his/her career development and that they take full advantage of the depth and breadth of the training opportunities offered.