Tri-Institutional Training in Vision Research

描述（由申请人提供）：康奈尔大学威尔医学院（原康奈尔大学医学院）、斯隆凯特林研究所和洛克菲勒大学这三所相邻机构的学院，请求资金继续九年前开始的视觉研究合作三机构培训计划。目前的TTPVR包括一整套针对博士生、博士后和医学生的培训活动。各院系的优势和多样性为视网膜细胞和发育生物学、遗传学、吞噬作用、分泌和内吞作用、神经再生、发育和可塑性、信号转导以及眼睛和大脑水平的信息处理提供了研究机会。各种各样的研究项目利用了大量的方法，如分子和细胞生物学、酵母和小鼠遗传学、基因转移和治疗、电生理学、成像、高分辨率光学显微镜、行为学、建模和流行病学。视觉培训资源的汇集使得项目的丰富程度超过了单个机构的项目，促进了参与的基础科学教师之间以及与临床教师之间的合作，并为雇用新的视觉教师或吸引现有教师参与视觉研究提供了独特的机会。课程教师和学生之间的互动通过视觉研讨会进行

DESCRIPTION (provided by applicant): Faculty of three contiguous institutions, Weill Medical College of Cornell University (formerly Cornell University Medical College), Sloan Kettering Institute, and The Rockefeller University, request funds to continue a collaborative tri-institutional training program in vision research started nine years ago. The current TTPVR consists of an integrated set of training activities for PhD students, postdoctoral fellows and medical students. The strengths and diversities of the faculties provide opportunities for research in retinal cell and developmental biology, genetics, phagocytosis, secretion and endocytosis, neural regeneration, development and plasticity, signal transduction, and information processing at the level of the eye and the brain. The various research projects utilize a vast array of methodologies, such as molecular and cell biology, yeast and mouse genetics, gene transfer and therapy, electrophysiology, imaging, high resolution optical microscopy, behavior, modeling, and epidemiology. The pooling of resources for vision training leads to an enrichment of programs over and above those available at the individual institutions, promotes collaborations between participating basic science faculty, as well as with clinical faculty, and provides a unique opportunity for the hiring of new Vision Faculty or attracting existing faculty into Vision Research. Interaction between Program Faculty and students takes place via a Vision seminar series and a Vision journal club, an annual post-ARVO poster session, through a course by clinical-academic faculty designed to expose basic vision scientists to vision disorders seen in the clinic and courses dealing with various aspects of vision research. This exposure provides a vehicle for a keener understanding of clinical problems and for the selection of research areas that unite clinical and basic scientists in the quest to cure blinding diseases. The request for NIH support of a proposed Tri-Institutional Training Program in Vision Research builds on major commitments by the participating institutions of faculty, funds and research space devoted to vision research.